Title |
Análisis MLVA y perfil de virulencia de aislamientos de Staphylococcus aureus resistentes a la meticilina adquiridos en la comunidad causantes de infecciones pediátricas en Paraguay
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Published in |
Revista Argentina de Microbiología, October 2017
|
DOI | 10.1016/j.ram.2017.03.012 |
Pubmed ID | |
Authors |
Fátima Rodríguez Acosta, Wilma D. Basualdo Acuña, Héctor Castro, Ana Campuzano, María L. Macchi, Juana Ortellado de Canese, Patricia Almada, Mónica Rodríguez, Lorena Grau, Gladys Velázquez, Carmen Espínola, Gloria C. Samudio Domínguez, Gloria Gómez, Letizia Carpinelli, Rosa M. Guillén Fretes |
Abstract |
Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is one of the first causes of skin and soft tissue infections, and can also produce severe diseases such as osteomyelitis and pneumonia. The aim of this descriptive study was to determine the SCCmec type and virulence profile and to study the genetic diversity by MLVA analysis of 21 CA-MRSA isolates that infected Paraguayan children in 2010. The SCCmec type and virulence factors were performed by PCR and genetic diversity by MLVA (multiple locus variable analysis). All the isolates carried SCCmec cassette iv. hla, hlb and sea genes were detected in 28,6%, 9,5% and 4,8% respectively. The MLVA analysis showed high genetic diversity with congruent antibiotic resistance and virulence profiles. This study revealed the presence of CA-MRSA harbouring SCCmeciv with high genetic diversity, providing information not available in our country. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Ireland | 1 | 33% |
United Kingdom | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 31 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 19% |
Student > Doctoral Student | 4 | 13% |
Student > Bachelor | 4 | 13% |
Student > Master | 3 | 10% |
Professor | 2 | 6% |
Other | 3 | 10% |
Unknown | 9 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 23% |
Biochemistry, Genetics and Molecular Biology | 5 | 16% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 6% |
Nursing and Health Professions | 2 | 6% |
Veterinary Science and Veterinary Medicine | 1 | 3% |
Other | 2 | 6% |
Unknown | 12 | 39% |