Title |
SARS-CoV-2 Infection and Placental Pathology
|
---|---|
Published in |
Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics, June 2021
|
DOI | 10.1055/s-0041-1730291 |
Pubmed ID | |
Authors |
Caio Ribeiro Vieira Leal, Rayra Amana Macêdo Maciel, Mário Dias Corrêa Júnior |
Abstract |
Placental pathophysiology in SARS-CoV-2 infection can help researchers understand more about the infection and its impact on the maternal/neonatal outcomes. This brief review provides an overview about some aspects of the placental pathology in SARS-CoV-2 infection. In total, 11 papers were included. The current literature suggests that there are no specific histopathological characteristics in the placenta related to SARS-CoV-2 infection, but placentas from infected women are more likely to show findings of maternal and/or fetal malperfusion. The most common findings in placentas from infected women were fibrin deposition and intense recruitment of inflammatory infiltrates. The transplacental transmission of this virus is unlikely to occur, probably due to low expression of the receptor for SARS-CoV-2 in placental cell types. Further studies are needed to improve our knowledge about the interaction between the virus and the mother-fetus dyad and the impact on maternal and neonatal/fetal outcomes. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 42 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 6 | 14% |
Researcher | 6 | 14% |
Student > Master | 3 | 7% |
Student > Doctoral Student | 2 | 5% |
Other | 2 | 5% |
Other | 1 | 2% |
Unknown | 22 | 52% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 19% |
Biochemistry, Genetics and Molecular Biology | 4 | 10% |
Nursing and Health Professions | 2 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Computer Science | 1 | 2% |
Other | 3 | 7% |
Unknown | 23 | 55% |