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Volume-dependent hemodynamic effects of blood collection in canine donors - evaluation of 13% and 15% of total blood volume depletion

Overview of attention for article published in Anais da Academia Brasileira de Ciências, February 2015
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Title
Volume-dependent hemodynamic effects of blood collection in canine donors - evaluation of 13% and 15% of total blood volume depletion
Published in
Anais da Academia Brasileira de Ciências, February 2015
DOI 10.1590/0001-3765201520140210
Pubmed ID
Authors

RUI R.F. FERREIRA, RAFAEL R. GOPEGUI, AUGUSTO J.F. DE MATOS

Abstract

Background: There is no consensus regarding the blood volume that could be safely donated by dogs, ranging from 11 to 25% of its total blood volume (TBV). No previous studies evaluated sedated donors. Aim: To evaluate the hemodynamic effects of blood collection from sedated and non-sedated dogs and to understand if such effects were volume-dependent. Materials and Methods: Fifty three donations of 13% of TBV and 20 donations of 15% TBV were performed in dogs sedated with diazepam and ketamine. Additionally, a total of 30 collections of 13% TBV and 20 collections of 15% TBV were performed in non-sedated dogs. Non-invasive arterial blood pressures and pulse rates were registered before and 15 min after donation. Results: Post-donation pulse rates increased significantly in both sedated groups, with higher differences in the 15% TBV collections. Systolic arterial pressures decreased significantly in these groups, while diastolic pressures increased significantly in 13% TBV donations. Non-sedated groups revealed a slight, but significant, SBP decrease. No clinical signs related to donations were registered. Conclusion: These results suggest that the collection of 15% TBV in sedated donors induces hemodynamic variations that may compromise the harmlessness of the procedure, while it seems to be a safe procedure in non-sedated dogs.

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The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 29%
Student > Bachelor 2 12%
Researcher 2 12%
Professor 1 6%
Other 1 6%
Other 0 0%
Unknown 6 35%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 5 29%
Agricultural and Biological Sciences 1 6%
Computer Science 1 6%
Psychology 1 6%
Medicine and Dentistry 1 6%
Other 1 6%
Unknown 7 41%