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X Demographics
Mendeley readers
| Title |
Efficacy of Topical 5% Acyclovir-1% Hydrocortisone Cream (ME-609) for Treatment of Herpes Labialis: a systematic review
|
|---|---|
| Published in |
Anais da Academia Brasileira de Ciências, August 2015
|
| DOI | 10.1590/0001-3765201520140701 |
| Pubmed ID | |
| Authors |
MARIA INÊS DA ROSA, SUÉLI L. SOUZA, BRUNA F. DE FARIAS, PATRÍCIA D.S. PIRES, EDUARDO R. DONDOSSOLA, MARIA EDUARDA F. DOS REIS |
| Abstract |
We performed a systematic review with the objective of verifying the efficacy of topical use 5% Acyclovir-1% Hydrocortisone cream compared to the placebo group for herpes simplex labialis treatment. We performed a literature search using MEDLINE, Embase, BIOSIS, LILACS, Scopus, Grey literature, the Cochrane Central Register of Controlled Trials, the ISI Web of Science and IBECS from 1990 to June 2014. We reported the outcomes using relative risk (RR) with 95% confidence intervals. The literature search yielded 180 potentially relevant publications. Reviews of the reference lists yielded two further citations. Among these papers, two were considered eligible for inclusion in this review. Both trials included 1,213 patients. A meta-analysis of these studies showed a RR = 0.77, (95% CI 0.70-0.86; p<0.001).This result suggests that an early episodic treatment with the combination of an antiviral and a steroid is beneficial for herpes simplex labialis treatment. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 30 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 8 | 27% |
| Student > Master | 6 | 20% |
| Student > Postgraduate | 4 | 13% |
| Student > Ph. D. Student | 3 | 10% |
| Professor | 2 | 7% |
| Other | 1 | 3% |
| Unknown | 6 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 10 | 33% |
| Medicine and Dentistry | 8 | 27% |
| Arts and Humanities | 1 | 3% |
| Mathematics | 1 | 3% |
| Agricultural and Biological Sciences | 1 | 3% |
| Other | 3 | 10% |
| Unknown | 6 | 20% |