Title |
Clinical predictors of cognitive impairment and psychiatric complications in Parkinson’s disease
|
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Published in |
Arquivos de Neuro-Psiquiatria, May 2015
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DOI | 10.1590/0004-282x20150016 |
Pubmed ID | |
Authors |
Lidiane S Campos, Rachel P Guimarães, Luiza G Piovesana, Paula C de Azevedo, Leonilda M B Santos, Anelyssa D'Abreu |
Abstract |
Objective To estimate the clinical and demographics aspects that may contribute to cognitive impairment and psychiatric symptoms in Parkinson's disease (PD). Method All patients answered a structured standardized clinical questionnaire. Two movement disorders specialists performed the following scale: Unified Parkinson's disease rating score (UPDRS), the modified Hoehn and Yahr staging, Schwab and England Scale, SCOPA cognition (SCOPA-COG), SCOPA-Psychiatric complications (SCOPA-PC) and Non-Motor Symptoms Scale (NMSS). We built a generalized linear model to assess predictors for the SCOPA-COG and SCOPA-PC scores. Results Almost 37% of our patients were demented as per SCOPA-COG scores. Level of education and the UPDRS-Subscale III were predictors of cognitive impairment. Higher scores in domain 3 of NMSS and male gender were associated with psychiatric complications as assessed per the SCOPA-PC. Conclusion Level of education and disease severity are predictors of dementia in PD. Psychiatric complications are more commonly observed in men. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 2% |
Unknown | 64 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 12 | 18% |
Student > Ph. D. Student | 9 | 14% |
Other | 6 | 9% |
Student > Doctoral Student | 5 | 8% |
Student > Master | 5 | 8% |
Other | 10 | 15% |
Unknown | 18 | 28% |
Readers by discipline | Count | As % |
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Psychology | 13 | 20% |
Medicine and Dentistry | 12 | 18% |
Neuroscience | 10 | 15% |
Nursing and Health Professions | 3 | 5% |
Sports and Recreations | 2 | 3% |
Other | 4 | 6% |
Unknown | 21 | 32% |