Title |
Malignant multiple sclerosis: clinical and demographic prognostic factors
|
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Published in |
Arquivos de Neuro-Psiquiatria, March 2017
|
DOI | 10.1590/0004-282x20170010 |
Pubmed ID | |
Authors |
Fabrício Hampshire-Araújo, Anke Bergmann, Regina Maria Papais Alvarenga, Cláudia Cristina Ferreira Vasconcelos |
Abstract |
Patients with malignant multiple sclerosis (MMS) reach a significant level of disability within a short period of time (Expanded Disability Status Scale score of 6 within five years). The clinical profile and progression of the disease were analyzed in a Brazilian cohort of 293 patients. Twenty-five (8,53%) patients were found to have MMS and were compared with the remaining 268 (91,47%). Women, non-white patients, older age at disease onset, shorter intervals between the first attacks, and more attacks in the first two years of the disease were all more common in the MMS group. These findings could serve as prognostic factors when making therapeutic decisions. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 36 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 8 | 22% |
Researcher | 5 | 14% |
Student > Master | 4 | 11% |
Student > Ph. D. Student | 4 | 11% |
Student > Doctoral Student | 2 | 6% |
Other | 5 | 14% |
Unknown | 8 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 28% |
Neuroscience | 5 | 14% |
Nursing and Health Professions | 4 | 11% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 6% |
Agricultural and Biological Sciences | 1 | 3% |
Other | 4 | 11% |
Unknown | 10 | 28% |