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MOG-IgG associated optic neuritis is not multiple sclerosis

Overview of attention for article published in Arquivos de Neuro-Psiquiatria, October 2017
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  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

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Title
MOG-IgG associated optic neuritis is not multiple sclerosis
Published in
Arquivos de Neuro-Psiquiatria, October 2017
DOI 10.1590/0004-282x20170121
Pubmed ID
Authors

Bruna Klein da Costa, Giordani Rodrigues dos Passos, Jefferson Becker, Douglas Kazutoshi Sato

Abstract

Autoantibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been reported in patients with inflammatory central nervous system disorders including isolated optic neuritis (ON). We compared our MOG-IgG ON patients with multiple sclerosis (MS) patients presenting with ON. Among the total of 38 patients with optic neuropathies, six patients with isolated ON were MOG-IgG positive and eight patients with ON fulfilled the diagnostic criteria for MS. All MS patients were negative for MOG-IgG using a cell-based assay. When compared with the MS group, the MOG-IgG patients were older (mean 47 years), more frequently male (ratio 2:1) and had a higher frequency of bilateral and/or recurrent ON. The brain magnetic resonance imaging of all MOG-IgG positive patients was normal or had only unspecific white matter T2 lesions. These findings suggest that MOG-IgG is a biomarker of an inflammatory demyelinating CNS disease distinct from MS.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 16%
Researcher 5 16%
Other 4 13%
Student > Master 3 9%
Student > Postgraduate 2 6%
Other 2 6%
Unknown 11 34%
Readers by discipline Count As %
Medicine and Dentistry 15 47%
Agricultural and Biological Sciences 2 6%
Biochemistry, Genetics and Molecular Biology 2 6%
Physics and Astronomy 1 3%
Neuroscience 1 3%
Other 0 0%
Unknown 11 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 November 2017.
All research outputs
#16,051,091
of 25,382,440 outputs
Outputs from Arquivos de Neuro-Psiquiatria
#684
of 1,369 outputs
Outputs of similar age
#188,166
of 331,218 outputs
Outputs of similar age from Arquivos de Neuro-Psiquiatria
#6
of 16 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,369 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,218 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.