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Mendeley readers
| Title |
The use of botulinum toxin type A in the treatment of HTLV-1-associated overactive bladder refractory to conventional therapy
|
|---|---|
| Published in |
Revista da Sociedade Brasileira de Medicina Tropical, August 2014
|
| DOI | 10.1590/0037-8682-0029-2014 |
| Pubmed ID | |
| Authors |
José Abraão Carneiro, Valéria Gusmão Bittencourt, Cassius de Oliveira, Rosana Andrade, Edgar Marcelino de Carvalho |
| Abstract |
Urinary symptoms occur in 19% of human T-cell lymphotropic virus type 1 (HTLV-1)-infected patients who do not fulfill criteria for HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and in almost 100% of HAM/TSP patients. Few studies have evaluated therapies for overactive bladder (OAB) caused by HTLV-1 infection. This case report describes the effect of onabotulinum toxin A on the urinary manifestations of three patients with HAM/TSP and OAB symptoms. The patients were intravesically administered 200 units of Botox®. Their incontinence episodes improved, and their OAB symptoms scores (OABSS) reduced significantly. These data indicate that Botox® should be a treatment option for OAB associated with HTLV-1 infection. |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 2 | 6% |
| Spain | 1 | 3% |
| Unknown | 28 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Postgraduate | 4 | 13% |
| Student > Bachelor | 4 | 13% |
| Student > Master | 4 | 13% |
| Other | 3 | 10% |
| Student > Ph. D. Student | 3 | 10% |
| Other | 7 | 23% |
| Unknown | 6 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 55% |
| Agricultural and Biological Sciences | 2 | 6% |
| Biochemistry, Genetics and Molecular Biology | 1 | 3% |
| Computer Science | 1 | 3% |
| Nursing and Health Professions | 1 | 3% |
| Other | 2 | 6% |
| Unknown | 7 | 23% |