Title |
Evaluation of the Commercial Kit SIRE Nitratase for detecting resistant Mycobacterium tuberculosis in Brazil
|
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Published in |
Revista da Sociedade Brasileira de Medicina Tropical, August 2017
|
DOI | 10.1590/0037-8682-0447-2016 |
Pubmed ID | |
Authors |
Silvana Spindola de Miranda, Isabela Neves de Almeida, Maria Luiza Lopes, Jamilly Dos Reis de Figueiredo, Lida Jouca de Assis Figueredo, Afrânio Lineu Kritski, Wânia da Silva Carvalho, Maria de Fátima Filardi Oliveira Mansur |
Abstract |
This study aimed to evaluate a new commercial kit, Kit SIRE Nitratase-PlastLabor, for testing the drug susceptibility of clinical Mycobacterium tuberculosis isolates. The accuracy of the Kit SIRE Nitratase was evaluated by examining the susceptibility (streptomycin, isoniazid, rifampicin, and ethambutol) of 40 M. tuberculosis isolates, using the proportion method with Lowenstein-Jensen medium or the BACTEC MGIT 960 system. The detection accuracy for streptomycin, isoniazid, rifampicin, and ethambutol was 95%, 97.5%, 100%, and 80%, respectively. The exceptional accuracy demonstrated by Kit SIRE Nitratase for isoniazid and rifampicin makes the kit an attractive option for screening M. tuberculosis strain resistance. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 50% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 28 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 5 | 18% |
Student > Bachelor | 4 | 14% |
Student > Ph. D. Student | 3 | 11% |
Student > Doctoral Student | 2 | 7% |
Professor | 1 | 4% |
Other | 1 | 4% |
Unknown | 12 | 43% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 4 | 14% |
Immunology and Microbiology | 3 | 11% |
Agricultural and Biological Sciences | 2 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Veterinary Science and Veterinary Medicine | 1 | 4% |
Other | 3 | 11% |
Unknown | 14 | 50% |