Title |
Potential overestimation of HIV-1 sub-subtype F1 circulation in Rio de Janeiro, Brazil
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Published in |
Memórias do Instituto Oswaldo Cruz, June 2018
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DOI | 10.1590/0074-02760170483 |
Pubmed ID | |
Authors |
Bianca Cristina Leires Marques, Mariza Gonçalves Morgado, Monick Lindenmeyer Guimarães |
Abstract |
In Brazil, detection of the HIV-1 sub-subtype F1 has decreased with a simultaneous increase in detection of the recombinant FB and FC forms. In previous HIV-1 env molecular epidemiology studies in Rio de Janeiro, 11.4% of the detected sequences were of the F1 sub-subtype. With the goal of re-estimating the prevalence of the HIV-1 F1 sub-subtype, we performed extended analyses of these samples by examining five genomic regions, resulting in 3.3% being confirmed as F1. Moreover, genomic analysis of 11 of the 21 samples identified as F1 confirmed that nine were F1 and two were BF1. Considering the number of samples assayed, the prevalence of F1 was quite low, which supports the use of different genomic regions for the assessment of HIV-1 classification in countries where several subtypes and recombinant forms co-circulate. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 16 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 3 | 19% |
Student > Bachelor | 3 | 19% |
Student > Doctoral Student | 2 | 13% |
Lecturer > Senior Lecturer | 1 | 6% |
Unspecified | 1 | 6% |
Other | 2 | 13% |
Unknown | 4 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 3 | 19% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 13% |
Social Sciences | 2 | 13% |
Immunology and Microbiology | 2 | 13% |
Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Other | 0 | 0% |
Unknown | 6 | 38% |