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Peeling the onion: the outer layers of Cryptococcus neoformans

Overview of attention for article published in Memórias do Instituto Oswaldo Cruz, May 2018
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Title
Peeling the onion: the outer layers of Cryptococcus neoformans
Published in
Memórias do Instituto Oswaldo Cruz, May 2018
DOI 10.1590/0074-02760180040
Pubmed ID
Authors

Daniel P Agustinho, Liza C Miller, Lucy X Li, Tamara L Doering

Abstract

Cryptococcus neoformans is an opportunistic fungal pathogen that is ubiquitous in the environment. It causes a deadly meningitis that is responsible for over 180,000 deaths worldwide each year, including 15% of all AIDS-related deaths. The high mortality rates for this infection, even with treatment, suggest a need for improved therapy. Unique characteristics of C. neoformans may suggest directions for drug discovery. These include features of three structures that surround the cell: the plasma membrane, the cell wall around it, and the outermost polysaccharide capsule. We review current knowledge of the fundamental biology of these fascinating structures and highlight open questions in the field, with the goal of stimulating further investigation that will advance basic knowledge and human health.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 81 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 16 20%
Student > Ph. D. Student 10 12%
Student > Master 10 12%
Student > Doctoral Student 4 5%
Professor 4 5%
Other 9 11%
Unknown 28 35%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 16%
Agricultural and Biological Sciences 10 12%
Immunology and Microbiology 7 9%
Chemistry 4 5%
Computer Science 2 2%
Other 12 15%
Unknown 33 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 May 2018.
All research outputs
#15,523,434
of 25,382,440 outputs
Outputs from Memórias do Instituto Oswaldo Cruz
#931
of 1,502 outputs
Outputs of similar age
#187,458
of 341,525 outputs
Outputs of similar age from Memórias do Instituto Oswaldo Cruz
#10
of 20 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,502 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,525 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.