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Fluoride-Releasing Materials to Prevent White Spot Lesions around Orthodontic Brackets: A Systematic Review

Overview of attention for article published in Brazilian Dental Journal, February 2016
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Title
Fluoride-Releasing Materials to Prevent White Spot Lesions around Orthodontic Brackets: A Systematic Review
Published in
Brazilian Dental Journal, February 2016
DOI 10.1590/0103-6440201600482
Pubmed ID
Authors

Patrícia Layane de Menezes Macêdo Nascimento, Micaelle Tenório Guedes Fernandes, Fabricio Eneas Diniz de Figueiredo, André Luis Faria-e-Silva

Abstract

The relation between orthodontic fixed appliances use and enamel demineralization is well established. Different preventive approaches have been suggested to this problem, but controversy remains about which is the best. The aim of this study was to perform a systematic review of clinical trials that investigated the effectiveness of materials containing fluorides to lute brackets or cover the bonding interface in order to inhibit the development and progression of white spot lesions. The null hypothesis was that fluoride materials do not affect the incidence of white spot lesions around brackets. A MEDLINE search was conducted for randomized clinical trials evaluating the development of white spot lesions in patients using fixed orthodontic appliances, followed by meta-analysis comparing the results for patients for whom dental materials containing fluorides were used (experimental group) to those for whom these materials were not used (control group). The pooled relative risk of developing white spot lesions for the experimental group was 0.42 (95% confidence interval: 0.25 to 0.72); hence, when fluoride-releasing materials are used, the patient has 58% less risk of white spot lesion development. Regarding white spot lesion extent, the pooled mean difference between the experimental and control groups was not statistically significant (-0.12; 95% confidence interval: -0.29 to 0.04). In conclusion, the results of the present systematic review suggest that fluoride-releasing materials can reduce the risk of white spot lesions around brackets. However, when white spot lesions had already occurred, there is no evidence that fluoride-releasing materials reduce the extent of these lesions.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Uruguay 1 1%
Unknown 87 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 20 23%
Student > Postgraduate 13 15%
Researcher 6 7%
Student > Doctoral Student 6 7%
Student > Ph. D. Student 6 7%
Other 15 17%
Unknown 22 25%
Readers by discipline Count As %
Medicine and Dentistry 58 66%
Pharmacology, Toxicology and Pharmaceutical Science 1 1%
Nursing and Health Professions 1 1%
Agricultural and Biological Sciences 1 1%
Unspecified 1 1%
Other 4 5%
Unknown 22 25%