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Mendeley readers
| Title |
Myocardial ischemic preconditioning upregulated protein 1(Mipu1):zinc finger protein 667 - a multifunctional KRAB/C2H2 zinc finger protein
|
|---|---|
| Published in |
Brazilian Journal of Medical and Biological Research, January 2015
|
| DOI | 10.1590/1414-431x20144029 |
| Pubmed ID | |
| Authors |
D. Han, C. Zhang, W.J. Fan, W.J. Pan, D.M. Feng, S.L. Qu, Z.S. Jiang |
| Abstract |
Myocardial ischemic preconditioning upregulated protein 1 (Mipu1) is a newly discovered upregulated gene produced in rats during the myocardial ischemic preconditioning process. Mipu1 cDNA contains a 1824-base pair open reading frame and encodes a 608 amino acid protein with an N-terminal Krüppel-associated box (KRAB) domain and classical zinc finger C2H2 motifs in the C-terminus. Mipu1 protein is located in the cell nucleus. Recent studies found that Mipu1 has a protective effect on the ischemia-reperfusion injury of heart, brain, and other organs. As a nuclear factor, Mipu1 may perform its protective function through directly transcribing and repressing the expression of proapoptotic genes to repress cell apoptosis. In addition, Mipu1 also plays an important role in regulating the gene expression of downstream inflammatory mediators by inhibiting the activation of activator protein-1 and serum response element. |
Mendeley readers
The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 18 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 4 | 22% |
| Student > Doctoral Student | 3 | 17% |
| Researcher | 3 | 17% |
| Student > Bachelor | 1 | 6% |
| Other | 1 | 6% |
| Other | 2 | 11% |
| Unknown | 4 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 6 | 33% |
| Biochemistry, Genetics and Molecular Biology | 4 | 22% |
| Agricultural and Biological Sciences | 3 | 17% |
| Sports and Recreations | 1 | 6% |
| Unknown | 4 | 22% |