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Low-protein diet does not alter reproductive, biochemical, and hematological parameters in pregnant Wistar rats

Overview of attention for article published in Brazilian Journal of Medical and Biological Research, January 2018
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Title
Low-protein diet does not alter reproductive, biochemical, and hematological parameters in pregnant Wistar rats
Published in
Brazilian Journal of Medical and Biological Research, January 2018
DOI 10.1590/1414-431x20186602
Pubmed ID
Authors

M.A.V. Barros, E.B. Andrade, R.G.N. Barros, I.K.M. Costa, I.C.L. Costa, G.F.A. Vitorino, J.J.C. Andrade, K.M. Paulino-Silva, V.O. Nogueira, J.L. de Brito Alves, J.H. Costa-Silva

Abstract

The aim of this study was to investigate the reproductive, biochemical, and hematological outcomes of pregnant rats exposed to protein restriction. Wistar rat dams were fed a control normal-protein (NP, 17% protein, n=8) or a low-protein (LP, 8% protein, n=14) diet from the 1st to the 20th day of pregnancy. On the 20th day, the clinical signs of toxicity were evaluated. The pregnant rats were then anesthetized and blood samples were collected for biochemical-hematological analyses, and laparotomy was performed to evaluate reproductive parameters. No sign of toxicity, or differences (P>0.05) in body weight gain and biochemical parameters (urea, creatinine, albumin, globulin, and total protein) between NP and LP pregnant dams were observed. Similarly, hematological data, including red blood cell count, white blood cell count, hemoglobin, hematocrit, red blood cell distribution width (coefficient of variation), mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, % lymphocytes, absolute lymphocyte count, platelet count, and mean platelet volume were similar (P>0.05) at the end of pregnancy. Reproductive parameters (the dam-offspring relationship, ovary mass, placenta mass, number of corpora lutea, implantation index, resorption index, and the pre- and post-implantation loss rates) were also not different (P>0.05) between NP and LP pregnant dams. The present data showed that a protein-restricted diet during pregnancy did not alter reproductive, biochemical, and hematological parameters and seems not to have any toxic effect on pregnant Wistar rats.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 14%
Student > Ph. D. Student 4 14%
Student > Bachelor 4 14%
Professor 2 7%
Student > Doctoral Student 1 4%
Other 1 4%
Unknown 12 43%
Readers by discipline Count As %
Medicine and Dentistry 3 11%
Nursing and Health Professions 3 11%
Agricultural and Biological Sciences 2 7%
Engineering 2 7%
Psychology 1 4%
Other 4 14%
Unknown 13 46%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2018.
All research outputs
#22,767,715
of 25,382,440 outputs
Outputs from Brazilian Journal of Medical and Biological Research
#1,018
of 1,254 outputs
Outputs of similar age
#389,382
of 449,583 outputs
Outputs of similar age from Brazilian Journal of Medical and Biological Research
#55
of 85 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,254 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 85 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.