Title |
Animal models of neurodegenerative diseases
|
---|---|
Published in |
Revista Brasileira de Psiquiatria, January 2013
|
DOI | 10.1590/1516-4446-2013-1157 |
Pubmed ID | |
Authors |
Fabíola Mara Ribeiro, Elizabeth Ribeiro da Silva Camargos, Leonardo Cruz de Souza, Antonio Lucio Teixeira |
Abstract |
The prevalence of neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD), increases with age, and the number of affected patients is expected to increase worldwide in the next decades. Accurately understanding the etiopathogenic mechanisms of these diseases is a crucial step for developing disease-modifying drugs able to preclude their emergence or at least slow their progression. Animal models contribute to increase the knowledge on the pathophysiology of neurodegenerative diseases. These models reproduce different aspects of a given disease, as well as the histopathological lesions and its main symptoms. The purpose of this review is to present the main animal models for AD, PD, and Huntington's disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 33% |
Germany | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | <1% |
Italy | 1 | <1% |
Belgium | 1 | <1% |
Spain | 1 | <1% |
United States | 1 | <1% |
Unknown | 127 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 25 | 19% |
Student > Master | 23 | 17% |
Student > Bachelor | 21 | 16% |
Researcher | 16 | 12% |
Student > Doctoral Student | 5 | 4% |
Other | 13 | 10% |
Unknown | 29 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 24 | 18% |
Neuroscience | 21 | 16% |
Biochemistry, Genetics and Molecular Biology | 18 | 14% |
Pharmacology, Toxicology and Pharmaceutical Science | 10 | 8% |
Medicine and Dentistry | 8 | 6% |
Other | 13 | 10% |
Unknown | 38 | 29% |