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Saliva, supragingival biofilm and root canals can harbor gene associated with resistance to lactamic agents

Overview of attention for article published in Brazilian Oral Research, March 2015
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Title
Saliva, supragingival biofilm and root canals can harbor gene associated with resistance to lactamic agents
Published in
Brazilian Oral Research, March 2015
DOI 10.1590/1807-3107bor-2015.vol29.0052
Pubmed ID
Authors

Ludmila Coutinho Moraes, Clarissa Cavalcanti Fatturi-Parolo, Maria Beatriz Cardoso Ferreira, Marcus Vinicius Reis Só, Francisco Montagner

Abstract

This study aimed to determine the presence of Prevotella strains and genes associated with resistance to lactamics in different oral niches from patients with/without primary endodontic infections. Saliva (S) and supragingival biofilm (SB) were collected from three patient groups: Group I - no endodontic infection (n = 15); Group II - acute endodontic infection (n = 12); and Group III - chronic endodontic infection (n = 15). Root canal (RC) samples were collected from Groups II and III. The presence of P. intermedia, P nigrescens, P. tannerae and cfxA/cfxA2 gene was assessed by PCR. The cfxA/cfxA2 gene was not detected in all environments within the same patient. The cfxA/cfxA2 gene was present in 23.81% of S samples, 28.57% of SB samples, and 7.41% of RC samples. Prevotella species were detected in 53.97%, 47.62% and 34.56% of the S, SB, and RC samples, respectively. P. intermedia had a high frequency in saliva samples from Group 3. Saliva samples from Group 1 had higher detection rates of P. nigrescens than did Groups 2 and 3. Patients without endodontic disease had high frequencies of P. nigrescens in the SB samples. The presence or absence of spontaneous symptoms was not related to the detection rates for resistance genes in the RC samples. Saliva, supragingival biofilm and root canals can harbor resistant bacteria. The presence of symptomatology did not increase the presence of the cfxA/cfxA2 gene in the supragingival biofilm and inside root canals.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 17%
Student > Postgraduate 4 17%
Student > Doctoral Student 3 13%
Student > Master 3 13%
Student > Bachelor 2 8%
Other 3 13%
Unknown 5 21%
Readers by discipline Count As %
Medicine and Dentistry 13 54%
Pharmacology, Toxicology and Pharmaceutical Science 2 8%
Veterinary Science and Veterinary Medicine 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Chemistry 1 4%
Other 2 8%
Unknown 4 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 July 2015.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Brazilian Oral Research
#296
of 509 outputs
Outputs of similar age
#216,917
of 291,961 outputs
Outputs of similar age from Brazilian Oral Research
#4
of 6 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 509 research outputs from this source. They receive a mean Attention Score of 2.3. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
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We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.