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Effects of the association of antifungal drugs on the antimicrobial action of endodontic sealers

Overview of attention for article published in Brazilian Oral Research, June 2015
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Title
Effects of the association of antifungal drugs on the antimicrobial action of endodontic sealers
Published in
Brazilian Oral Research, June 2015
DOI 10.1590/1807-3107bor-2015.vol29.0073
Pubmed ID
Authors

Paulo Henrique Weckwerth, Fellipe Lombardo de Souza Lima, Vanessa Raquel Greatti, Marco Antonio Hungaro Duarte, Rodrigo Ricci Vivan

Abstract

This in vitro study aimed to determine the susceptibility of oral specimens and ATCC lineages of Candida albicans for five endodontic sealers, which were pure and associated with two antifungal drugs, and to analyze their effect on the physical properties. For this purpose, 30 lineages of C. albicans, collected from the oral cavity of patients assisted at the endodontics clinic of the Universidade Sagrado Coração, were analyzed. Yeasts susceptibility to the sealers was tested by diffusion on agar plates. Physical properties were evaluated according to the ADA specification no. 57. The pure versions of the Sealer 26, AH Plus, Endofill, Fillapex, and Sealapex demonstrated antifungal activity, with Endofill presenting the greatest inhibition zones. All cements, except for Endofill, had their antifungal actions enhanced by addition of ketoconazole and fluconazole (p < 0.05), and the AH Plus presented the best antifungal activity. The addition of antifungal drugs did not interfere with the setting time and flowability of the sealers. It was concluded that the addition of antifungals to endodontic sealers enhanced the antimicrobial action of most cements tested without altering their physical properties.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 14%
Student > Postgraduate 3 14%
Student > Master 3 14%
Researcher 2 9%
Professor > Associate Professor 1 5%
Other 1 5%
Unknown 9 41%
Readers by discipline Count As %
Medicine and Dentistry 6 27%
Social Sciences 2 9%
Biochemistry, Genetics and Molecular Biology 1 5%
Veterinary Science and Veterinary Medicine 1 5%
Nursing and Health Professions 1 5%
Other 0 0%
Unknown 11 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 June 2015.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from Brazilian Oral Research
#296
of 509 outputs
Outputs of similar age
#192,850
of 264,138 outputs
Outputs of similar age from Brazilian Oral Research
#6
of 16 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 509 research outputs from this source. They receive a mean Attention Score of 2.3. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,138 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.