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Impaired flow-mediated dilation response and carotid intima-media thickness in patients with type 1 diabetes mellitus with a mean disease duration of 4.1 years

Overview of attention for article published in Archives of Endocrinology and Metabolism, July 2017
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Title
Impaired flow-mediated dilation response and carotid intima-media thickness in patients with type 1 diabetes mellitus with a mean disease duration of 4.1 years
Published in
Archives of Endocrinology and Metabolism, July 2017
DOI 10.1590/2359-3997000000281
Pubmed ID
Authors

Lúcia Helena Bonalume Tacito, Antonio Carlos Pires, Juan Carlos Yugar-Toledo

Abstract

This study aimed at assessing the endothelial function in patients with Type 1 diabetes (T1DM) using flow-mediated dilation (FMD) response and carotid artery intima-media thickness (CIMT). This study enrolled 32 T1DM patients (mean disease duration 4.1 years) and 28 age-matched controls (CTL Group). Endothelial function and CIMT were assessed with high-resolution ultrasound using standardized offline measurements. FMD was significantly lower in patients in the T1DM Group (8.9 ± 3.2%) compared with those in the CTL Group (13.3 ± 4.3%; P-value < 0.0001). Similarly, CIMT differed significantly between T1DM patients (0.525 ± 0.03 mm) and controls (0.508 ± 0.03 mm; P-value = 0.041). Even though, the values are within the normal range for age. Patients with T1DM have impaired endothelial function characterized by reduced FMD when compared to controls. However, vascular remodeling as seen by increases in CIMT was not found in this study.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 3 15%
Student > Postgraduate 3 15%
Lecturer 2 10%
Other 2 10%
Student > Master 2 10%
Other 6 30%
Unknown 2 10%
Readers by discipline Count As %
Medicine and Dentistry 11 55%
Agricultural and Biological Sciences 2 10%
Arts and Humanities 1 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Nursing and Health Professions 1 5%
Other 2 10%
Unknown 2 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2018.
All research outputs
#20,660,571
of 25,382,440 outputs
Outputs from Archives of Endocrinology and Metabolism
#529
of 800 outputs
Outputs of similar age
#250,792
of 324,713 outputs
Outputs of similar age from Archives of Endocrinology and Metabolism
#5
of 5 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 800 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 19th percentile – i.e., 19% of its peers scored the same or lower than it.
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