Luiz Gonzaga Vaz COELHO, James Ramalho MARINHO, Robert GENTA, Laercio Tenório RIBEIRO, Maria do Carmo Friche PASSOS, Schlioma ZATERKA, Paulo Pimentel ASSUMPÇÃO, Alfredo José A BARBOSA, Ricardo BARBUTI, Lucia Libanês BRAGA, Helenice BREYER, Aloisio CARVALHAES, Décio CHINZON, Marcelo CURY, Gerson DOMINGUES, Jorge Luiz JORGE, Ismael MAGUILNIK, Frederico Passos MARINHO, Joaquim Prado de MORAES-FILHO, José Miguel Luz PARENTE, Celso Mirra de PAULA-E-SILVA, José PEDRAZZOLI-JÚNIOR, Ana Flávia Passos RAMOS, Heinrich SEIDLER, José Nonato SPINELLI, José Vitor ZIR

Significant progress has been obtained since the III Brazilian Consensus Conference on H. pylori infection held in 2012, in Bento Gonçalves, Brazil, and justify a fourth meeting to establish updated guidelines on the current management of H. pylori infection. Therefore, the Núcleo Brasileiro para Estudo do Helicobacter pylori e Microbiota (NBEHPM), association linked to Brazilian Federation of Gastroenterology (FBG) held its fourth meeting again in Bento Gonçalves, RS, Brazil, on August 25-27, 2017. Twenty-six delegates, including gastroenterologists, endoscopists, and pathologists from the five regions of Brazil as well as one international guest from the United States, participated in the meeting. The participants were invited based on their knowledge and contribution to the study of H. pylori infection. The meeting sought to review different aspects of treatment for infection; establish a correlation between infection, dyspepsia, intestinal microbiota changes, and other disorders with a special emphasis on gastric cancer; and reassess the epidemiological and diagnostic aspects of H. pylori infection. Participants were allocated into four groups as follows: 1) Epidemiology and Diagnosis, 2) Dyspepsia, intestinal microbiota and other afections, 3) Gastric Cancer, and, 4) Treatment. Before the consensus meeting, participants received a topic to be discussed and prepared a document containing a recent literature review and statements that should be discussed and eventually modified during the face-to-face meeting. All statements were evaluated in two rounds of voting. Initially, each participant discussed the document and statements with his group for possible modifications and voting. Subsequently, during a second voting in a plenary session in the presence of all participants, the statements were voted upon and eventually modified. The participants could vote using five alternatives: 1) strongly agree; 2) partially agree; 3) undecided; 4) disagree; and 5) strongly disagree. The adopted consensus index was that 80% of the participants responded that they strongly or partially agreed with each statement. The recommendations reported are intended to provide the most current and relevant evidences to management of H. pylori infection in adult population in Brazil.