Title |
Refractory gastroesophageal reflux disease
|
---|---|
Published in |
Arquivos de Gastroenterologia, January 2013
|
DOI | 10.1590/s0004-28032012000400012 |
Pubmed ID | |
Authors |
Joaquim Prado P Moraes-Filho |
Abstract |
Gastroesophageal reflux disease (GERD) is a condition which develops when the reflux of stomach contents causes troublesome symptoms and/or complications. Its pathophysiology, diagnosis and treatment have frequently been analyzed but it is interesting to review some aspects of the GERD refractory patients to the proton pump inhibitors treatment. The treatment encompasses behavioral measures and pharmacological therapy. The majority of the patients respond well to proton pump inhibitors treatment but 20%-42% of them may not do so well. Patients who are unresponsible to 4-8 weeks' treatment with proton pump inhibitors (omeprazole, pantoprazole, rabeprazole, lansoprazole, esomeprazole, pantoprazole-Mg) might have so-called refractory GERD. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 2% |
Honduras | 1 | 2% |
Unknown | 44 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 24% |
Student > Master | 7 | 15% |
Student > Bachelor | 5 | 11% |
Student > Doctoral Student | 3 | 7% |
Other | 3 | 7% |
Other | 10 | 22% |
Unknown | 7 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 25 | 54% |
Nursing and Health Professions | 5 | 11% |
Biochemistry, Genetics and Molecular Biology | 2 | 4% |
Agricultural and Biological Sciences | 2 | 4% |
Immunology and Microbiology | 1 | 2% |
Other | 2 | 4% |
Unknown | 9 | 20% |