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Relation between fatigue and autonomic disturbances in multiple sclerosis

Overview of attention for article published in Arquivos de Neuro-Psiquiatria, September 2007
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Title
Relation between fatigue and autonomic disturbances in multiple sclerosis
Published in
Arquivos de Neuro-Psiquiatria, September 2007
DOI 10.1590/s0004-282x2007000400023
Pubmed ID
Authors

Andréa Temponi Lebre, Maria Fernanda Mendes, Charles P. Tilbery, Ana Lucia Almeida, Argemiro Scatolini Neto

Abstract

Fatigue is a common symptom in multiple sclerosis (MS). The objective of this study was to relate fatigue and autonomic disturbances in MS. Fifty patients with MS relapsing remitting clinical form participated in this study. Thirty three (66%) were women and 17 (34%) men. Score less or equal to 3.5 in the EDSS. Five non invasive cardiovascular tests were applied in all patients for the sympathetic and parasympathetic evaluation. The results obtained in the hand grip test were increased in the blood pressure of 14.62 +/- 9.13 mmHg for the group with fatigue and of 21.68 +/- 7.18 mmHg for the non fatigue group. This difference was statistically significant (p<0.05). Conclusion is that there is a loss in the capacity to increase blood pressure in patients with fatigue suggesting a sympathetic dysfunction.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 25%
Professor > Associate Professor 2 17%
Student > Ph. D. Student 1 8%
Student > Doctoral Student 1 8%
Student > Bachelor 1 8%
Other 1 8%
Unknown 3 25%
Readers by discipline Count As %
Medicine and Dentistry 4 33%
Neuroscience 2 17%
Agricultural and Biological Sciences 1 8%
Sports and Recreations 1 8%
Nursing and Health Professions 1 8%
Other 0 0%
Unknown 3 25%