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Mechanism of action of sodium hypochlorite

Overview of attention for article published in Brazilian Dental Journal, April 2003
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#4 of 284)
  • High Attention Score compared to outputs of the same age (95th percentile)

Mentioned by

news
1 news outlet
twitter
1 X user
patent
1 patent
facebook
1 Facebook page
wikipedia
1 Wikipedia page

Citations

dimensions_citation
448 Dimensions

Readers on

mendeley
888 Mendeley
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Title
Mechanism of action of sodium hypochlorite
Published in
Brazilian Dental Journal, April 2003
DOI 10.1590/s0103-64402002000200007
Pubmed ID
Authors

Carlos Estrela, Cyntia R.A. Estrela, Eduardo Luis Barbin, Júlio César E. Spanó, Melissa A. Marchesan, Jesus D. Pécora

Abstract

The choice of an irrigating solution for use in infected root canals requires previous knowledge of the microorganisms responsible for the infectious process as well as the properties of different irrigating solutions. Complex internal anatomy, host defenses and microorganism virulence are important factors in the treatment of teeth with asymptomatic apical periodontitis. Irrigating solutions must have expressive antimicrobial action and tissue dissolution capacity. Sodium hypochlorite is the most used irrigating solution in endodontics, because its mechanism of action causes biosynthetic alterations in cellular metabolism and phospholipid destruction, formation of chloramines that interfere in cellular metabolism, oxidative action with irreversible enzymatic inactivation in bacteria, and lipid and fatty acid degradation. The aim of this work is to discuss the mechanism of action of sodium hypochlorite based on its antimicrobial and physico-chemical properties.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 888 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 3 <1%
Germany 1 <1%
Netherlands 1 <1%
Italy 1 <1%
Zimbabwe 1 <1%
United Kingdom 1 <1%
Peru 1 <1%
Belgium 1 <1%
Spain 1 <1%
Other 1 <1%
Unknown 876 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 141 16%
Student > Bachelor 118 13%
Student > Postgraduate 100 11%
Student > Ph. D. Student 56 6%
Student > Doctoral Student 56 6%
Other 130 15%
Unknown 287 32%
Readers by discipline Count As %
Medicine and Dentistry 322 36%
Agricultural and Biological Sciences 88 10%
Engineering 30 3%
Biochemistry, Genetics and Molecular Biology 30 3%
Chemistry 29 3%
Other 86 10%
Unknown 303 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 June 2023.
All research outputs
#2,252,211
of 25,463,091 outputs
Outputs from Brazilian Dental Journal
#4
of 284 outputs
Outputs of similar age
#2,743
of 63,136 outputs
Outputs of similar age from Brazilian Dental Journal
#1
of 2 outputs
Altmetric has tracked 25,463,091 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 284 research outputs from this source. They receive a mean Attention Score of 2.6. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 63,136 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them