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Bone quality associated with daily intake of coffee: a biochemical, radiographic and histometric study

Overview of attention for article published in Brazilian Dental Journal, September 2010
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2 X users
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1 Facebook page
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1 YouTube creator

Citations

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48 Mendeley
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Title
Bone quality associated with daily intake of coffee: a biochemical, radiographic and histometric study
Published in
Brazilian Dental Journal, September 2010
DOI 10.1590/s0103-64402010000300004
Pubmed ID
Authors

Suzie Aparecida Lacerda, Renata Inahara Matuoka, Rander Moreira Macedo, Sergio Olavo Petenusci, Alessandra Aparecida Campos, Luiz Guilherme Brentegani

Abstract

Caffeine induces loss of calcium and influences the normal development of bone. This study investigated the effects of coffee on bone metabolism in rats by biochemical measurement of calcium, bone densitometry and histometry. Male rats, born of female treated daily with coffee and with coffee intake since born, were anesthetized, subjected to extraction of the upper right incisor, and sacrificed 7, 21 and 42 days after surgery. Blood and urine samples were taken, and their maxilla radiographed and processed to obtain 5-µm-thick semi-serial sections stained with hematoxylin and eosin. The volume and bone quality were estimated using an image-analysis software. The results showed significantly greater amount of calcium in the plasma (9.40 ± 1.73 versus 9.80 ± 2.05 mg%) and urine (1.00 ± 0.50 versus 1.25 ± 0.70 mg/24 h) and significantly less amount in bone (90.0 ± 1.94 versus 86.0 ± 2.12 mg/mg bone), reduced bone mineral density (1.05 ± 0.11 versus 0.65 ± 0.15 mmAL), and lower amount of bone (76.19 ± 1.6 versus 53.41 ± 2.1 %) (ANOVA; p≤0.01) in animals treated with coffee sacrificed after 42 days. It may be concluded that coffee/caffeine intake caused serious adverse effects on calcium metabolism in rats, including increased levels of calcium in the urine and plasma, decreased bone mineral density and lower volume of bone, thus delaying the bone repair process.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 48 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 21%
Student > Bachelor 8 17%
Researcher 6 13%
Student > Doctoral Student 3 6%
Other 3 6%
Other 6 13%
Unknown 12 25%
Readers by discipline Count As %
Medicine and Dentistry 22 46%
Agricultural and Biological Sciences 4 8%
Nursing and Health Professions 3 6%
Environmental Science 2 4%
Biochemistry, Genetics and Molecular Biology 1 2%
Other 4 8%
Unknown 12 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 October 2022.
All research outputs
#16,721,717
of 25,374,647 outputs
Outputs from Brazilian Dental Journal
#98
of 284 outputs
Outputs of similar age
#84,812
of 104,800 outputs
Outputs of similar age from Brazilian Dental Journal
#3
of 6 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 284 research outputs from this source. They receive a mean Attention Score of 2.6. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,800 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.