| Title |
A importância dos níveis de vitamina D nas doenças autoimunes
|
|---|---|
| Published in |
Revista Brasileira de Reumatologia, February 2010
|
| DOI | 10.1590/s0482-50042010000100007 |
| Pubmed ID | |
| Authors | |
| Abstract |
In addition to its role in calcium homeostasis, it is believed that the active form of vitamin D has immunomodulatory effects on cells of the immune system, particularly T lymphocytes, as well as on the production and action of several cytokines. The interaction of vitamin D with the immune system has been the target of a growing number of publications in recent years. Current studies have linked the deficiency of vitamin D with different autoimmune diseases, including insulin-dependent diabetes mellitus (IDDM), multiple sclerosis (MS), inflammatory bowel disease (IBD), systemic lupus erythematosus (SLE), and rheumatoid arthritis (RA). This article reviews the physiology and immunomodulatory role of vitamin D, emphasizing its involvement in rheumatic diseases such as SLE and RA. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 3 | 27% |
| United States | 1 | 9% |
| Portugal | 1 | 9% |
| Unknown | 6 | 55% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 11 | 100% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Kenya | 1 | <1% |
| Egypt | 1 | <1% |
| Unknown | 204 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 62 | 30% |
| Student > Master | 30 | 15% |
| Student > Postgraduate | 18 | 9% |
| Student > Ph. D. Student | 13 | 6% |
| Student > Doctoral Student | 11 | 5% |
| Other | 27 | 13% |
| Unknown | 45 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 87 | 42% |
| Nursing and Health Professions | 17 | 8% |
| Agricultural and Biological Sciences | 17 | 8% |
| Biochemistry, Genetics and Molecular Biology | 15 | 7% |
| Immunology and Microbiology | 8 | 4% |
| Other | 13 | 6% |
| Unknown | 49 | 24% |