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Comparison of red cell distribution width and a red cell discriminant function incorporating volume dispersion for distinguishing iron deficiency from beta thalassemia trait in patients with…

Overview of attention for article published in Sao Paulo Medical Journal, October 1996
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Title
Comparison of red cell distribution width and a red cell discriminant function incorporating volume dispersion for distinguishing iron deficiency from beta thalassemia trait in patients with microcytosis
Published in
Sao Paulo Medical Journal, October 1996
DOI 10.1590/s1516-31801996000500005
Pubmed ID
Authors

Carmen Silvia Passos Lima, Aparecida Ribeiro de Carvalho Reis, Helena Zerlotti Wolf Grotto, Sara Teresinha Ollala Saad, Fernando Ferreira Costa

Abstract

The red cell distribution width (RDW), and another red cell discriminant function incorporating RDW (MCV2 x RDW/Hgb x 100) were determined in a group of 30 patients with iron deficiency anemia, 30 patients with beta thalassemia trait, and 30 normal subjects. Both RDW and (MCV2 x RDW/Hgb x 100) mean values were significantly higher in iron deficiency anemia than in beta thalassemia trait (p < 0.001). Taking RDW equal or above 21.0 percent among microcytic anemia patients, we identified correctly 90.0 percent of patients with iron deficiency anemia. The sensitivity and specificity of the test were 90.0 percent (IC 95 percent: 0.75-0.98) and 77.0 percent (IC 95 percent: 0.60-0.88), respectively. RDW values below 21.0 percent identified correctly 77.0 percent of beta thalassemia trait with a sensitivity and a specificity of 77.0 percent (IC 95 percent: 0.60-0.88) and 90.0 percent (IC 95 percent: 0.75-0.96), respectively. Taking values of (MCV2 x RDW/Hgb x 100) above and below 80.0 percent as indicative of iron deficiency and beta thalassemia trait, respectively, we identified correctly 97.0 percent of those patients in each group. Both sensitivity and specificity were 97.0 percent (IC 95 percent: 0.84-0.99). These results indicated that the red cell discriminant function incorporating volume dispersion (MCV2 x RDW/Hgb x 100) is a highly sensitive and specific method in the initial screening of patients with microcytic anemia and is better than RDW in differentiating iron deficiency anemia from beta thalassemia trait.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 2 22%
Student > Bachelor 2 22%
Professor > Associate Professor 2 22%
Researcher 1 11%
Other 1 11%
Other 0 0%
Unknown 1 11%
Readers by discipline Count As %
Medicine and Dentistry 5 56%
Agricultural and Biological Sciences 2 22%
Nursing and Health Professions 2 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 September 2009.
All research outputs
#8,783,469
of 25,986,827 outputs
Outputs from Sao Paulo Medical Journal
#4
of 13 outputs
Outputs of similar age
#8,747
of 27,338 outputs
Outputs of similar age from Sao Paulo Medical Journal
#1
of 1 outputs
Altmetric has tracked 25,986,827 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13 research outputs from this source. They receive a mean Attention Score of 3.5. This one scored the same or higher as 9 of them.
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We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them