Title |
Spinal cord compression in <FONT FACE=Symbol>b</font>-thalassemia: follow-up after radiotherapy
|
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Published in |
Sao Paulo Medical Journal, November 1998
|
DOI | 10.1590/s1516-31801998000600009 |
Pubmed ID | |
Authors |
Silvana Fahel da Fonseca, Maria Stella Figueiredo, Rodolfo Delfini Cançado, Fernando Nakandakare, Roberto Segreto, José Kerbauy |
Abstract |
Spinal cord compression due to extramedullary hematopoiesis is a well-described but rare syndrome encountered in several clinical hematologic disorders, including beta-thalassemia. We report the case of a patient with intermediate beta-thalassemia and crural paraparesis due to spinal cord compression by a paravertebral extramedullary mass. She was successfully treated with low-dose radiotherapy and transfusions. After splenectomy, she was regularly followed up for over four years without transfusion or recurrence of spinal cord compression. Extramedullary hematopoiesis should be investigated in patients with hematologic disorders and spinal cord symptoms. The rapid recognition and treatment with radiotherapy can dramatically alleviate symptoms. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Italy | 1 | 9% |
Unknown | 10 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 2 | 18% |
Lecturer > Senior Lecturer | 1 | 9% |
Student > Doctoral Student | 1 | 9% |
Professor | 1 | 9% |
Student > Ph. D. Student | 1 | 9% |
Other | 2 | 18% |
Unknown | 3 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 45% |
Biochemistry, Genetics and Molecular Biology | 1 | 9% |
Social Sciences | 1 | 9% |
Agricultural and Biological Sciences | 1 | 9% |
Unknown | 3 | 27% |