Title |
Comparative analysis of preemptive analgesic effect of dexamethasone and diclofenac following third molar surgery
|
---|---|
Published in |
Brazilian Oral Research, April 2013
|
DOI | 10.1590/s1806-83242013005000012 |
Pubmed ID | |
Authors |
José Leonardo Simone, Waldyr Antonio Jorge, Anna Carolina Ratto Tempestini Horliana, Talita Girio Canaval, Isabel Peixoto Tortamano |
Abstract |
The objective of the study was to compare the analgesic effectiveness of dexamethasone and diclofenac sodium administered preemptively after surgical removal of third molars. Forty-four ASA (American Society of Anesthesiologists) I patients (19 men, 35 women; 16-28 years old) randomly and double-blindly received diclofenac sodium (50 mg) or dexamethasone (8 mg) or placebo 1 h before surgery. Intensity of pain, measured with a visual analog scale (VAS), was the variable studied at different postoperative times (1 h, 2 h, 3 h, 6 h, 8 h, 12 h, 48 h, 4 d and 7 d). The total amount of rescue medication (TARM) ingested (paracetamol) was another variable of the study. The Kruskal-Wallis statistical test was used. A p value of < .05 was adopted to reject the null hypothesis. The dexamethasone group showed lower pain intensity (p < .05) than the diclofenac sodium and placebo groups (p < .05). No difference in TARM was observed among the groups (p < .05). Preemptively administered, dexamethasone was effective in controlling postoperative pain. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 93 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 19 | 20% |
Student > Postgraduate | 8 | 9% |
Student > Ph. D. Student | 8 | 9% |
Student > Bachelor | 8 | 9% |
Student > Doctoral Student | 7 | 8% |
Other | 12 | 13% |
Unknown | 31 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 43 | 46% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
Nursing and Health Professions | 3 | 3% |
Agricultural and Biological Sciences | 2 | 2% |
Environmental Science | 1 | 1% |
Other | 3 | 3% |
Unknown | 38 | 41% |