Title |
Biological agents: investigation into leprosy and other infectious diseases before indication
|
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Published in |
Anais Brasileiros de Dermatologia, December 2013
|
DOI | 10.1590/abd1806-4841.20132187 |
Pubmed ID | |
Authors |
João Roberto Antônio, Rosa Maria Cordeiro Soubhia, Vania Del Arco Paschoal, Carolina Forte Amarante, Ana Regina Franchi Travolo |
Abstract |
Biological agents are widely used for various immune-mediated diseases, with remarkable effectiveness in the treatment of rheumatoid arthritis (RA), psoriasis, psoriatic arthritis, ankylosing spondylitis and Crohn's disease. However, attention needs to be drawn to the adverse effects of these therapies and the risk of reactivating underlying granulomatous infectious diseases such as tuberculosis, leprosy, syphilis, leishmaniasis, among others. The objective of this paper is to describe a case of leprosy in a patient with RA using anti-TNF alfa, demonstrating the need for systematic investigation of skin lesions suggestive of leprosy in patients who require rheumatoid arthritis therapeutic treatment, especially in endemic regions like Brazil. |
X Demographics
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United Kingdom | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 40 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 1 | 3% |
Other | 1 | 3% |
Student > Postgraduate | 1 | 3% |
Unknown | 37 | 93% |
Readers by discipline | Count | As % |
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Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Medicine and Dentistry | 1 | 3% |
Unknown | 38 | 95% |