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Adenosine: an endogenous mediator in the pathogenesis of psoriasis

Overview of attention for article published in Anais Brasileiros de Dermatologia, December 2015
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Title
Adenosine: an endogenous mediator in the pathogenesis of psoriasis
Published in
Anais Brasileiros de Dermatologia, December 2015
DOI 10.1590/abd1806-4841.20153689
Pubmed ID
Authors

Moira Festugato

Abstract

It is known that inflammatory and immune responses protect us from the invasion of micro-organisms and eliminate "wastes" from the injured sites, but they may also be responsible for significant tissue damage. Adenosine, as a purine nucleoside, which is produced in inflamed or injured sites, fulfills its role in limiting tissue damage. Although, it may have a pleiotropic effect, which signals it with a proinflammatory state in certain situations, it can be considered a potent anti-inflammatory mediator. The effects of adenosine, which acts through its receptors on T cell, on mast cell and macrophages, on endothelial cells, on neutrophils and dendritic cells, as they indicate TNF-alpha and cytokines, show that this mediator has a central role in the pathogenesis of psoriasis. The way it acts in psoriasis will be reviewed in this study.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 3 14%
Student > Master 3 14%
Student > Ph. D. Student 3 14%
Other 2 9%
Researcher 2 9%
Other 2 9%
Unknown 7 32%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 4 18%
Medicine and Dentistry 3 14%
Nursing and Health Professions 2 9%
Agricultural and Biological Sciences 2 9%
Environmental Science 1 5%
Other 3 14%
Unknown 7 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 January 2016.
All research outputs
#17,729,864
of 25,988,468 outputs
Outputs from Anais Brasileiros de Dermatologia
#4
of 6 outputs
Outputs of similar age
#243,071
of 398,052 outputs
Outputs of similar age from Anais Brasileiros de Dermatologia
#6
of 9 outputs
Altmetric has tracked 25,988,468 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6 research outputs from this source. They receive a mean Attention Score of 1.7. This one scored the same or higher as 2 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 398,052 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.