Title |
Diphencyprone as a therapeutic option in cutaneous metastasis of melanoma. A single-institution experience*
|
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Published in |
Anais Brasileiros de Dermatologia, March 2018
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DOI | 10.1590/abd1806-4841.20187162 |
Pubmed ID | |
Authors |
Ivana Lameiras Gibbons, Marina Sonagli, Eduardo Bertolli, Mariana Petaccia de Macedo, Clovis Antonio Lopes Pinto, João Pedreira Duprat |
Abstract |
Diphencyprone has been reported as a local immunotherapy for cutaneous melanoma metastases. We aim to report cases of melanoma patients treated with diphencyprone in a single Brazilian institution and highlight their outcomes. Since 2012, we have treated 16 melanoma patients with cutaneous metastases with topical diphencyprone. To date, we have had 37.5% of complete response, 25% of partial responses, and 31.25% patients without any response. Treatment was well tolerated and local toxicity was easily controlled. We believe topical diphencyprone is a feasible treatment that can be another option for treating melanoma patients, especially in cases of in-transit or extensive disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 5 | 24% |
Other | 4 | 19% |
Student > Ph. D. Student | 2 | 10% |
Student > Master | 2 | 10% |
Student > Bachelor | 1 | 5% |
Other | 2 | 10% |
Unknown | 5 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 52% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 10% |
Nursing and Health Professions | 2 | 10% |
Social Sciences | 1 | 5% |
Unknown | 5 | 24% |