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Diphencyprone as a therapeutic option in cutaneous metastasis of melanoma. A single-institution experience*

Overview of attention for article published in Anais Brasileiros de Dermatologia, March 2018
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Title
Diphencyprone as a therapeutic option in cutaneous metastasis of melanoma. A single-institution experience*
Published in
Anais Brasileiros de Dermatologia, March 2018
DOI 10.1590/abd1806-4841.20187162
Pubmed ID
Authors

Ivana Lameiras Gibbons, Marina Sonagli, Eduardo Bertolli, Mariana Petaccia de Macedo, Clovis Antonio Lopes Pinto, João Pedreira Duprat

Abstract

Diphencyprone has been reported as a local immunotherapy for cutaneous melanoma metastases. We aim to report cases of melanoma patients treated with diphencyprone in a single Brazilian institution and highlight their outcomes. Since 2012, we have treated 16 melanoma patients with cutaneous metastases with topical diphencyprone. To date, we have had 37.5% of complete response, 25% of partial responses, and 31.25% patients without any response. Treatment was well tolerated and local toxicity was easily controlled. We believe topical diphencyprone is a feasible treatment that can be another option for treating melanoma patients, especially in cases of in-transit or extensive disease.

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Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 5 24%
Other 4 19%
Student > Ph. D. Student 2 10%
Student > Master 2 10%
Student > Bachelor 1 5%
Other 2 10%
Unknown 5 24%
Readers by discipline Count As %
Medicine and Dentistry 11 52%
Pharmacology, Toxicology and Pharmaceutical Science 2 10%
Nursing and Health Professions 2 10%
Social Sciences 1 5%
Unknown 5 24%