Title |
Sensibilidad a fosfomicina en Escherichia coli productoras de betalactamasas de espectro extendido
|
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Published in |
Revista Peruana de Medicina Experimental y Salud Pública, March 2018
|
DOI | 10.17843/rpmesp.2018.351.3566 |
Pubmed ID | |
Authors |
Sheyber J Lifonzo-Mucha, Paula E Tamariz-Zamudio, Roky G Champi-Merino |
Abstract |
Urinary infections are caused mainly by Escherichia coli (E. coli); indiscriminate use of antibiotics has caused an increase in infections due to extended-spectrum beta-lactamase (ESBL)-producing strains. Aiming to determine the sensitivity to fosfomycin, a study was conducted in ESBL-producing E. coli strains isolated from urine cultures at a hospital in Peru. Two hundred and sixty-six (266) strains of E. coli were collected, which were determined by conventional methods to be ESBL- producing. Sensitivity to fosfomycin was determined through minimum inhibitory concentration with the agar dilution method and the diffusion disc method. One hundred and ninety-two (192) (72.2%) strains of ESBL-producing E. coli strains sensitive to Fosfomycin were found. It, therefore, follows that fosfomycin exhibits antimicrobial activity against ESBL-producing E. coli strains and that it could be considered a good treatment option for resistant strains. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 15 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 2 | 13% |
Researcher | 2 | 13% |
Student > Master | 2 | 13% |
Student > Postgraduate | 1 | 7% |
Unknown | 8 | 53% |
Readers by discipline | Count | As % |
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Immunology and Microbiology | 2 | 13% |
Veterinary Science and Veterinary Medicine | 1 | 7% |
Biochemistry, Genetics and Molecular Biology | 1 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 7% |
Nursing and Health Professions | 1 | 7% |
Other | 1 | 7% |
Unknown | 8 | 53% |