Title |
Importance of early detection of hemoglobinopathies in the pediatric population in developing countries.
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Published in |
Revista chilena de pediatría, August 2020
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DOI | 10.32641/rchped.vi91i4.1438 |
Pubmed ID | |
Authors |
Marisol Aguirre, Diego Medina, María Valeria Araujo, María Alejandra Campo, Andrés Castro, Liliana Fernández-Trujillo, Mercedes Alcalá, Luz Fernanda Sua |
Abstract |
The objective of this study is to spread awareness among health personnel about the importance of early detection of hemoglobinopathies since it is the most frequent monogenic recessive disorder worldwide. Retrospective study of the results of capillary electropho resis (CE) of 152 patients aged between 0 and 18 years who were evaluated in 2017 due to suspected hemoglobinopathies in a University Hospital in Colombia. The information was collected from me dical records and the Hematology and Hemostasis Laboratory, ensuring data privacy and approved by the local Ethics Committee. Of 152 patients, 48.6% were aged between 7 and 18. The frequency of hemoglobinopathies was 42.7%. The most frequent hemoglobin variant was the sickle cell trait (Hb S) with 14.5%. The hematologist was the professional who most frequently requested CE. We found that hemoglobinopathies are usually diagnosed late in pediatric patients. This may favor complications and progression of the disease and increase healthcare costs. More information and education are required for general physicians and pediatricians in order to achieve early diagnosis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 27 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 5 | 19% |
Other | 2 | 7% |
Student > Master | 2 | 7% |
Lecturer | 1 | 4% |
Unspecified | 1 | 4% |
Other | 2 | 7% |
Unknown | 14 | 52% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 7 | 26% |
Nursing and Health Professions | 2 | 7% |
Unspecified | 1 | 4% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Agricultural and Biological Sciences | 1 | 4% |
Other | 1 | 4% |
Unknown | 14 | 52% |