Title |
An exclusively based parenteral fish-oil emulsion reverses cholestasis.
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Published in |
Nutrición Hospitalaria, October 2014
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DOI | 10.3305/nh.2015.31.1.8284 |
Pubmed ID | |
Authors |
Miryam Triana Junco, Natalia García Vázquez, Carlos Zozaya, Marta Ybarra Zabala, Steven Abrams, Abelardo García de Lorenzo, Miguel Sáenz de Pipaón Marcos |
Abstract |
Prolonged parenteral nutrition (PN) leads to liver damage. Recent interest has focused on the lipid component of PN. A lipid emulsion based on w-3 fatty acids decrease conjugated bilirubin. A mixed lipid emulsion derived from soybean, coconut, olive, and fish oils reverses jaundice. Here we report the reversal of cholestasis and the improvement of enteral feeding tolerance in 1 infant with intestinal failure-associated liver disease. Treatment involved the substitution of a mixed lipid emulsion with one containing primarily omega-3 fatty acids during 37 days. Growth and biochemical tests of liver function improved significantly. This suggests that fat emulsions made from fish oils may be more effective means of treating this condition compared with an intravenous lipid emulsion containing soybean oil, medium -chain triglycerides, olive oil, and fish oil. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 17 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 1 | 6% |
Student > Postgraduate | 1 | 6% |
Unknown | 15 | 88% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 1 | 6% |
Medicine and Dentistry | 1 | 6% |
Unknown | 15 | 88% |