Title |
Terbinafine-induced liver toxicity in the context of a SARS-CoV-2 pandemic: a case report.
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Published in |
Revista de Gastroenterología del Perú, June 2021
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DOI | 10.47892/rgp.2021.412.1280 |
Pubmed ID | |
Authors |
Carla Bustios Sanchez, Julia Sumire Umeres, Carmen Asato Higa, Victor Monge Zapata |
Abstract |
Terbinafine is a drug that can induce acute liver damage. We present the case of a 40-year-old male patient who developed liver dysfunction after 35 days of terbinafine treatment for onychomycosis. The anatomopathological study showed: acute hepatitis in resolution, in addition to ductopenia and cholestasis. These findings, without a history of viral or autoimmune hepatitis, are consistent with the diagnosis of drug-induced liver damage (DILI). In this report we present the first case in our country of a patient who is affected by an acute liver disease: terbinafine-induced liver injury, to which SARS-CoV-2 infection was later associated in the context of a pandemic. |
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