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Comparison of intravitreal ranibizumab and bevacizumab treatment for retinopathy of prematurity

Overview of attention for article published in Arquivos Brasileiros de Oftalmologia, January 2015
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Title
Comparison of intravitreal ranibizumab and bevacizumab treatment for retinopathy of prematurity
Published in
Arquivos Brasileiros de Oftalmologia, January 2015
DOI 10.5935/0004-2749.20150090
Pubmed ID
Authors

Muhammet Kazim Erol, Deniz Turgut Coban, Esin Sogutlu Sari, Ahmet Burak Bilgin, Berna Dogan, Ozdemir Ozdemir, Zuhal Ozen Tunay

Abstract

To compare the efficacy of intravitreal ranibizumab and bevacizumab treatment for type 1 retinopathy of prematurity (ROP). 36 eyes of 20 patients with type 1 ROP who received anti-vascular endothelial growth factor (anti-VEGF) intravitreal injections between August 2011 and February 2013 were retrospectively evaluated. Fifteen eyes of 8 patients received 0.25 mg ranibizumab (group 1), and 21 eyes of 12 patients received 0.625 mg bevacizumab (group 2). Eyes were examined by indirect ophthalmoscopy on the first day, third day, first week, and first month and as required after injections. Laser photocoagulation was performed in cases with progression of ROP. The mean gestation time was 26.2 ± 2.7 weeks in group 1 patients and 27.1 ± 2.5 weeks in group 2 patients. No statistical difference in the time of gestation was observed between the two groups. The mean follow-up period was 20 ± 4.5 months. Laser photocoagulation was performed in 6 of 15 eyes from group 1 and 2 of 21 eyes from group 2. No eyes developed retinal detachment during the follow-up period. Ranibizumab and bevacizumab showed an efficacy in the treatment of type 1 ROP. The incidence of disease relapse was higher in eyes which received ranibizumab. Further randomized, controlled clinical trials are required to compare the efficacy of ranibizumab and bevacizumab.

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Mendeley readers

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Geographical breakdown

Country Count As %
Canada 1 2%
Unknown 46 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 17%
Student > Doctoral Student 7 15%
Other 5 11%
Researcher 5 11%
Professor > Associate Professor 4 9%
Other 9 19%
Unknown 9 19%
Readers by discipline Count As %
Medicine and Dentistry 26 55%
Nursing and Health Professions 3 6%
Agricultural and Biological Sciences 2 4%
Biochemistry, Genetics and Molecular Biology 1 2%
Social Sciences 1 2%
Other 1 2%
Unknown 13 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2015.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from Arquivos Brasileiros de Oftalmologia
#322
of 446 outputs
Outputs of similar age
#306,533
of 359,528 outputs
Outputs of similar age from Arquivos Brasileiros de Oftalmologia
#28
of 52 outputs
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So far Altmetric has tracked 446 research outputs from this source. They receive a mean Attention Score of 2.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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