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Cardiovascular Autonomic Dysfunction in Patients with Morbid Obesity

Overview of attention for article published in Arquivos Brasileiros de Cardiologia, November 2015
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Title
Cardiovascular Autonomic Dysfunction in Patients with Morbid Obesity
Published in
Arquivos Brasileiros de Cardiologia, November 2015
DOI 10.5935/abc.20150125
Pubmed ID
Authors

Maurício de Sant Anna, João Regis Ivar Carneiro, Renata Ferreira Carvalhal, Diego de Faria Magalhães Torres, Gustavo Gavina da Cruz, José Carlos do Vale Quaresma, Jocemir Ronaldo Lugon, Fernando Silva Guimarães

Abstract

Morbid obesity is directly related to deterioration in cardiorespiratory capacity, including changes in cardiovascular autonomic modulation. This study aimed to assess the cardiovascular autonomic function in morbidly obese individuals. Cross-sectional study, including two groups of participants: Group I, composed by 50 morbidly obese subjects, and Group II, composed by 30 nonobese subjects. The autonomic function was assessed by heart rate variability in the time domain (standard deviation of all normal RR intervals [SDNN]; standard deviation of the normal R-R intervals [SDNN]; square root of the mean squared differences of successive R-R intervals [RMSSD]; and the percentage of interval differences of successive R-R intervals greater than 50 milliseconds [pNN50] than the adjacent interval), and in the frequency domain (high frequency [HF]; low frequency [LF]: integration of power spectral density function in high frequency and low frequency ranges respectively). Between-group comparisons were performed by the Student's t-test, with a level of significance of 5%. Obese subjects had lower values of SDNN (40.0 ± 18.0 ms vs. 70.0 ± 27.8 ms; p = 0.0004), RMSSD (23.7 ± 13.0 ms vs. 40.3 ± 22.4 ms; p = 0.0030), pNN50 (14.8 ± 10.4 % vs. 25.9 ± 7.2%; p = 0.0061) and HF (30.0 ± 17.5 Hz vs. 51.7 ± 25.5 Hz; p = 0.0023) than controls. Mean LF/HF ratio was higher in Group I (5.0 ± 2.8 vs. 1.0 ± 0.9; p = 0.0189), indicating changes in the sympathovagal balance. No statistical difference in LF was observed between Group I and Group II (50.1 ± 30.2 Hz vs. 40.9 ± 23.9 Hz; p = 0.9013). morbidly obese individuals have increased sympathetic activity and reduced parasympathetic activity, featuring cardiovascular autonomic dysfunction.

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Mendeley readers

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The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 43 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 4 9%
Student > Postgraduate 3 7%
Student > Master 2 5%
Student > Doctoral Student 1 2%
Professor 1 2%
Other 0 0%
Unknown 32 74%
Readers by discipline Count As %
Nursing and Health Professions 4 9%
Medicine and Dentistry 3 7%
Sports and Recreations 2 5%
Biochemistry, Genetics and Molecular Biology 2 5%
Unknown 32 74%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 November 2015.
All research outputs
#22,760,732
of 25,374,917 outputs
Outputs from Arquivos Brasileiros de Cardiologia
#1,002
of 1,210 outputs
Outputs of similar age
#253,619
of 296,418 outputs
Outputs of similar age from Arquivos Brasileiros de Cardiologia
#8
of 10 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,210 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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