Children and adolescents with congenital heart disease often have alterations in their exercise capacity that can be evaluated by various functional testing.
To evaluate the functional capacity of children and adolescents with congenital heart disease (CHD) with systematic review and meta-analyses.
The review included observational studies, data from the first evaluation of randomized clinical trials or observational follow-up periods after clinical trials which evaluated functional capacity by cardiopulmonary exercise test, stress testing, six-minute walk test or step test, in children and adolescents with CHD, aged between six and 18 years, and comparisons with healthy controls in the same age group. The quantitative assessment was performed by meta-analysis, by comparing the maximal oxygen consumption (VO2max) of children and adolescents with CHD and respective control groups.
Twenty-five of 2.683 studies identified in the search met the inclusion criteria. The VO2max measurement showed that patients with CHD have a decrease of 9.31 ml/Kg/min (95% CI. -12.48 to -6.13; I2, 94.3%, P for heterogeneity < 0.001) compared with the control group. The meta-analysis of the data of maximum heart rate (HR) reached during cardiopulmonary test and stress testing, retrieved from 18 studies, showed a HR value of -15.14 bpm (95% CI. -20.97 to -9.31; I2, 94.3%, P for heterogeneity < 0.001) compared with the control group.
Children and adolescents with CHD have lower VO2max and HR compared to controls.
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 August 2024.
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#8,746,740
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Outputs from Arquivos Brasileiros de Cardiologia
#295
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Outputs of similar age
#111,977
of 332,569 outputs
Outputs of similar age from Arquivos Brasileiros de Cardiologia
#1
of 19 outputs
Altmetric has tracked 29,400,575 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 1,685 research outputs from this source. They receive a mean Attention Score of 4.6. This one has done well, scoring higher than 81% of its peers.
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We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.
