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Estrogen deficiency in ovariectomized rats: can resistance training re-establish angiogenesis in visceral adipose tissue?

Overview of attention for article published in Clinics, September 2016
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Title
Estrogen deficiency in ovariectomized rats: can resistance training re-establish angiogenesis in visceral adipose tissue?
Published in
Clinics, September 2016
DOI 10.6061/clinics/2016(09)08
Pubmed ID
Authors

Camila do Valle Gomes-Gatto, Fernanda Oliveira Duarte, Uliana Sbeguen Stotzer, Maria Fernanda Cury Rodrigues, Sérgio Eduardo de Andrade Perez, Heloisa Sobreiro Selistre-de-Araujo

Abstract

The purpose of this study was to investigate the effects of resistance training on angiogenesis markers of visceral adipose tissue in ovariectomized rats. Adult Sprague-Dawley female rats were divided into four groups (n=6 per group): sham-sedentary, ovariectomized sedentary, sham-resistance training and ovariectomized resistance training. The rats were allowed to climb a 1.1-m vertical ladder with weights attached to their tails and the weights were progressively increased. Sessions were performed three times per week for 10 weeks. Visceral adipose tissue angiogenesis and morphology were analyzed by histology. VEGF-A mRNA and protein levels were analyzed by real-time PCR and ELISA, respectively. Ovariectomy resulted in higher body mass (p=0.0003), adipocyte hypertrophy (p=0.0003), decreased VEGF-A mRNA (p=0.0004) and protein levels (p=0.0009), and decreased micro-vascular density (p=0.0181) in the visceral adipose tissue of the rats. Resistance training for 10 weeks was not able to attenuate the reduced angiogenesis in the visceral adipose tissue of the ovariectomized rats. Our findings indicate that the resistance training program used in this study could not ameliorate low angiogenesis in the visceral adipose tissue of ovariectomized rats.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 37 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 32%
Student > Doctoral Student 3 8%
Unspecified 2 5%
Student > Bachelor 2 5%
Professor 2 5%
Other 6 16%
Unknown 10 27%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 14%
Sports and Recreations 4 11%
Medicine and Dentistry 4 11%
Nursing and Health Professions 3 8%
Unspecified 2 5%
Other 5 14%
Unknown 14 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2016.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from Clinics
#1,001
of 1,215 outputs
Outputs of similar age
#308,501
of 348,369 outputs
Outputs of similar age from Clinics
#6
of 10 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,215 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.