Title |
Emergence of plasmid-mediated colistin resistance (MCR-1) among Escherichia coli isolated from South African patients
|
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Published in |
South African Medical Journal, April 2016
|
DOI | 10.7196/samj.2016.v106i5.10710 |
Pubmed ID | |
Authors |
Jennifer Coetzee, Craig Corcoran, Elizabeth Prentice, Mischka Moodley, Marc Mendelson, Laurent Poirel, Patrice Nordmann, Adrian John Brink |
Abstract |
The polymyxin antibiotic colistin is an antibiotic of last resort for the treatment of extensively drug-resistant Gram-negative bacteria, including carbapenemase-producing Enterobacteriaceae. The State of the World's Antibiotics report in 2015 highlighted South Africa (SA)'s increasing incidence of these 'superbugs' (3.2% of Klebsiella pneumoniae reported from SA were carbapenemase producers), and in doing so, underscored SA's increasing reliance on colistin as a last line of defence. Colistin resistance effectively renders such increasingly common infections untreatable. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Venezuela, Bolivarian Republic of | 1 | 25% |
United Kingdom | 1 | 25% |
Australia | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 98 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 18 | 18% |
Researcher | 11 | 11% |
Student > Ph. D. Student | 10 | 10% |
Student > Bachelor | 10 | 10% |
Student > Postgraduate | 5 | 5% |
Other | 16 | 16% |
Unknown | 28 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 15 | 15% |
Agricultural and Biological Sciences | 14 | 14% |
Immunology and Microbiology | 11 | 11% |
Biochemistry, Genetics and Molecular Biology | 11 | 11% |
Veterinary Science and Veterinary Medicine | 4 | 4% |
Other | 7 | 7% |
Unknown | 36 | 37% |