Title |
Positive 14-3-3 and tau proteins in a sporadic Creutzfeldt-Jakob disease case and a brief perspective of prion diseases in Colombia
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Published in |
Biomédica, February 2016
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DOI | 10.7705/biomedica.v36i3.2729 |
Pubmed ID | |
Authors |
Kevin Escandón-Vargas, Andrés Zorrilla-Vaca, Raúl Heli Corral-Prado |
Abstract |
Prion diseases are rare neurodegenerative disorders occurring worldwide and affecting both humans and animals. Herein, we present the case of a patient diagnosed with definite sporadic Creutzfeldt-Jakob disease in Cali, Colombia. Besides neurological examination, 14-3-3 and tau proteins were valuable tools supporting the diagnosis. We also present a brief perspective of the prion diseases reported in Colombia to date. Although the incidence of prion diseases is unknown in Colombia, our literature review revealed that one case of scrapie in 1981 and 29 human sporadic cases of Creutzfeldt-Jakob disease have been documented and published in our country. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Colombia | 2 | 25% |
Venezuela, Bolivarian Republic of | 2 | 25% |
United States | 1 | 13% |
Unknown | 3 | 38% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 88% |
Scientists | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Brazil | 1 | 4% |
Unknown | 23 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 25% |
Student > Master | 4 | 17% |
Student > Ph. D. Student | 3 | 13% |
Student > Postgraduate | 3 | 13% |
Student > Bachelor | 3 | 13% |
Other | 1 | 4% |
Unknown | 4 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 33% |
Agricultural and Biological Sciences | 2 | 8% |
Nursing and Health Professions | 1 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Psychology | 1 | 4% |
Other | 3 | 13% |
Unknown | 8 | 33% |