Title |
Family History of Myocardial Infarction Is a Risk Factor for Venous Thromboembolism Among Whites But Not Among Blacks
|
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Published in |
Clinical and Applied Thrombosis/Hemostasis, June 2012
|
DOI | 10.1177/1076029612448419 |
Pubmed ID | |
Authors |
Fatima D. Mili, W. Craig Hooper, Cathy Lally, Harland Austin |
Abstract |
In addition to potentially sharing common pathogenesis and clinical manifestations, venous and arterial thromboses might have overlapping risk factors. To evaluate the family history of myocardial infarction (MI) as a risk factor for venous thromboembolism (VTE) among whites and blacks, we analyze data from the Genetic Attributes and Thrombosis Epidemiology (GATE) study. Results indicate that the association between VTE and a family history of MI is statistically significant only among whites (odds ratio [OR] = 1.3; 95% confidence interval [CI] = 1.03-1.8), particularly when they have diabetes mellitus (OR = 3.1; 95% CI = 1.2-8.0). Among blacks, the association between VTE and a family history of MI is not statistically significant (OR = 1.2; 95% CI = 0.89-1.5) either among those with diabetes or those without diabetes. We conclude that a family history of MI is a risk factor for VTE among certain populations stratified by race and comorbid conditions. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 3 | 75% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Spain | 1 | 11% |
Unknown | 8 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 2 | 22% |
Other | 2 | 22% |
Researcher | 2 | 22% |
Student > Bachelor | 1 | 11% |
Unknown | 2 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 5 | 56% |
Nursing and Health Professions | 1 | 11% |
Biochemistry, Genetics and Molecular Biology | 1 | 11% |
Unknown | 2 | 22% |