Title |
Selecting postoperative adjuvant systemic therapy for early stage breast cancer: A critical assessment of commercially available gene expression assays
|
---|---|
Published in |
Seminars in Surgical Oncology, February 2017
|
DOI | 10.1002/jso.24561 |
Pubmed ID | |
Authors |
David M. Hyams, Eric Schuur, Javier Angel Aristizabal, Juan Enrique Bargallo Rocha, Cesar Cabello, Roberto Elizalde, Laura García‐Estévez, Henry L. Gomez, Artur Katz, Aníbal Nuñez De Pierro |
Abstract |
Risk stratification of patients with early stage breast cancer may support adjuvant chemotherapy decision-making. This review details the development and validation of six multi-gene classifiers, each of which claims to provide useful prognostic and possibly predictive information for early stage breast cancer patients. A careful assessment is presented of each test's analytical validity, clinical validity, and clinical utility, as well as the quality of evidence supporting its use. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Guatemala | 1 | 20% |
Mexico | 1 | 20% |
United Kingdom | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 80% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 58 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 8 | 14% |
Researcher | 7 | 12% |
Student > Master | 7 | 12% |
Student > Bachelor | 6 | 10% |
Student > Postgraduate | 5 | 9% |
Other | 9 | 16% |
Unknown | 16 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 21 | 36% |
Biochemistry, Genetics and Molecular Biology | 7 | 12% |
Agricultural and Biological Sciences | 3 | 5% |
Nursing and Health Professions | 2 | 3% |
Computer Science | 1 | 2% |
Other | 6 | 10% |
Unknown | 18 | 31% |