| Title |
Highly Pathogenic Avian Influenza A(H5N1) Viruses at the Animal-Human Interface in Vietnam, 2003-2010.
|
|---|---|
| Published in |
Journal of Infectious Diseases, September 2017
|
| DOI | 10.1093/infdis/jix003 |
| Pubmed ID | |
| Authors |
Adrian Creanga, Nguyen Le Khanh Hang, Vuong Duc Cuong, Ha T Nguyen, Hoang Vu Mai Phuong, Le Thi Thanh, Nguyen Co Thach, Pham Thi Hien, Nguyen Tung, Yunho Jang, Amanda Balish, Nguyen Hoang Dang, Mai Thuy Duong, Ngo Thu Huong, Do Ngoc Hoa, Nguyen Dang Tho, Alexander Klimov, Bryan K Kapella, Larisa Gubareva, James C Kile, Nguyen Tran Hien, Le Quynh Mai, C Todd Davis |
| Abstract |
Mutation and reassortment of highly pathogenic avian influenza A(H5N1) viruses at the animal-human interface remain a major concern for emergence of viruses with pandemic potential. To understand the relationship of H5N1 viruses circulating in poultry and those isolated from humans, comprehensive phylogenetic and molecular analyses of viruses collected from both hosts in Vietnam between 2003 and 2010 were performed. We examined the temporal and spatial distribution of human cases relative to H5N1 poultry outbreaks and characterized the genetic lineages and amino acid substitutions in each gene segment identified in humans relative to closely related viruses from avian hosts. Six hemagglutinin clades and 8 genotypes were identified in humans, all of which were initially identified in poultry. Several amino acid mutations throughout the genomes of viruses isolated from humans were identified, indicating the potential for poultry viruses infecting humans to rapidly acquire molecular markers associated with mammalian adaptation and antiviral resistance. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 29 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 7 | 24% |
| Student > Master | 6 | 21% |
| Student > Bachelor | 4 | 14% |
| Lecturer | 1 | 3% |
| Professor | 1 | 3% |
| Other | 4 | 14% |
| Unknown | 6 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 6 | 21% |
| Immunology and Microbiology | 4 | 14% |
| Medicine and Dentistry | 3 | 10% |
| Agricultural and Biological Sciences | 3 | 10% |
| Environmental Science | 1 | 3% |
| Other | 4 | 14% |
| Unknown | 8 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 February 2021.
All research outputs
#7,206,686
of 25,377,790 outputs
Outputs from Journal of Infectious Diseases
#6,245
of 14,793 outputs
Outputs of similar age
#105,505
of 325,227 outputs
Outputs of similar age from Journal of Infectious Diseases
#76
of 153 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 14,793 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.4. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 325,227 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 153 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.