Title |
Spanish guidelines for the management of autosomal dominant polycystic kidney disease *
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Published in |
Nephrology Dialysis Transplantation, August 2014
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DOI | 10.1093/ndt/gfu186 |
Pubmed ID | |
Authors |
Elisabet Ars, Carmen Bernis, Gloria Fraga, Víctor Martínez, Judith Martins, Alberto Ortiz, José Carlos Rodríguez-Pérez, Laia Sans, Roser Torra, on behalf of the Spanish Working Group on Inherited Kidney Disease |
Abstract |
Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent cause of genetic renal disease and accounts for 6-10% of patients on renal replacement therapy (RRT). Very few prospective, randomized trials or clinical studies address the diagnosis and management of this relatively frequent disorder. No clinical guidelines are available to date. This is a consensus statement presenting the recommendations of the Spanish Working Group on Inherited Kidney Diseases, which were agreed to following a literature search and discussions. Levels of evidence found were C and D according to the Centre for Evidence-Based Medicine (University of Oxford). The recommendations relate to, among other topics, the use of imaging and genetic diagnosis, management of hypertension, pain, cyst infections and bleeding, extra-renal involvement including polycystic liver disease and cranial aneurysms, management of chronic kidney disease (CKD) and RRT and management of children with ADPKD. Recommendations on specific ADPKD therapies are not provided since no drug has regulatory approval for this indication. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 8% |
Spain | 1 | 8% |
India | 1 | 8% |
Ecuador | 1 | 8% |
Unknown | 8 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 9 | 75% |
Practitioners (doctors, other healthcare professionals) | 3 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 3 | 3% |
United States | 1 | <1% |
Unknown | 105 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 20 | 18% |
Researcher | 17 | 16% |
Student > Bachelor | 12 | 11% |
Student > Postgraduate | 9 | 8% |
Student > Ph. D. Student | 8 | 7% |
Other | 22 | 20% |
Unknown | 21 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 57 | 52% |
Nursing and Health Professions | 6 | 6% |
Biochemistry, Genetics and Molecular Biology | 4 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 4% |
Agricultural and Biological Sciences | 3 | 3% |
Other | 9 | 8% |
Unknown | 26 | 24% |