| Title |
Ethical, social, and cultural issues related to clinical genetic testing and counseling in low- and middle-income countries: a systematic review
|
|---|---|
| Published in |
Genetics in Medicine, August 2018
|
| DOI | 10.1038/s41436-018-0090-9 |
| Pubmed ID | |
| Authors |
Adrina Zhong, Benedict Darren, Bethina Loiseau, Li Qun Betty He, Trillium Chang, Jessica Hill, Helen Dimaras |
| Abstract |
We performed a systematic review of the ethical, social, and cultural issues associated with delivery of genetic services in low- and middle-income countries (LMICs). We searched 11 databases for studies addressing ethical, social, and/or cultural issues associated with clinical genetic testing and/or counselling performed in LMICs. Narrative synthesis was employed to analyze findings, and resultant themes were mapped onto the social ecological model (PROSPERO #CRD42016042894). After reviewing 13,308 articles, 192 met inclusion criteria. Nine themes emerged: (1) genetic counseling has a tendency of being directive, (2) genetic services have psychosocial consequences that require improved support, (3) medical genetics training is inadequate, (4) genetic services are difficult to access, (5) social determinants affect uptake and understanding of genetic services, (6) social stigma is often associated with genetic disease, (7) family values are at risk of disruption by genetic services, (8) religious principles pose barriers to acceptability and utilization of genetic services, and (9) cultural beliefs and practices influence uptake of information and understanding of genetic disease. We identified a number of complex and interrelated ethical, cultural, and social issues with implications implications for further development of genetic services in LMICs. |
X Demographics
The data shown below were collected from the profiles of 35 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 6 | 17% |
| Canada | 4 | 11% |
| Australia | 3 | 9% |
| Colombia | 2 | 6% |
| United Kingdom | 2 | 6% |
| Poland | 1 | 3% |
| Indonesia | 1 | 3% |
| Portugal | 1 | 3% |
| Saudi Arabia | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 13 | 37% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 22 | 63% |
| Scientists | 7 | 20% |
| Practitioners (doctors, other healthcare professionals) | 5 | 14% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 138 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 19 | 14% |
| Student > Master | 15 | 11% |
| Student > Ph. D. Student | 12 | 9% |
| Unspecified | 9 | 7% |
| Student > Postgraduate | 9 | 7% |
| Other | 27 | 20% |
| Unknown | 47 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 22 | 16% |
| Biochemistry, Genetics and Molecular Biology | 13 | 9% |
| Unspecified | 9 | 7% |
| Social Sciences | 9 | 7% |
| Nursing and Health Professions | 8 | 6% |
| Other | 23 | 17% |
| Unknown | 54 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 April 2023.
All research outputs
#1,750,541
of 25,670,640 outputs
Outputs from Genetics in Medicine
#588
of 2,956 outputs
Outputs of similar age
#35,235
of 342,408 outputs
Outputs of similar age from Genetics in Medicine
#21
of 72 outputs
Altmetric has tracked 25,670,640 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,956 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 19.0. This one has done well, scoring higher than 80% of its peers.
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We're also able to compare this research output to 72 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.