| Title |
Practice Bulletin No. 162
|
|---|---|
| Published in |
Obstetrics & Gynecology, May 2016
|
| DOI | 10.1097/aog.0000000000001405 |
| Pubmed ID | |
| Abstract |
Prenatal genetic diagnostic testing is intended to determine, with as much certainty as possible, whether a specific genetic disorder or condition is present in the fetus. In contrast, prenatal genetic screening is designed to assess whether a patient is at increased risk of having a fetus affected by a genetic disorder. Originally, prenatal genetic testing focused primarily on Down syndrome (trisomy 21), but now it is able to detect a broad range of genetic disorders. Although it is necessary to perform amniocentesis or chorionic villus sampling (CVS) to definitively diagnose most genetic disorders, in some circumstances, fetal imaging with ultrasonography, echocardiography, or magnetic resonance imaging may be diagnostic of a particular structural fetal abnormality that is suggestive of an underlying genetic condition.The objective of prenatal genetic testing is to detect health problems that could affect the woman, fetus, or newborn and provide the patient and her obstetrician-gynecologist or other obstetric care provider with enough information to allow a fully informed decision about pregnancy management. Prenatal genetic testing cannot identify all abnormalities or problems in a fetus, and any testing should be focused on the individual patient's risks, reproductive goals, and preferences. It is important that patients understand the benefits and limitations of all prenatal screening and diagnostic testing, including the conditions for which tests are available and the conditions that will not be detected by testing. It also is important that patients realize that there is a broad range of clinical presentations, or phenotypes, for many genetic disorders and that results of genetic testing cannot predict all outcomes. Prenatal genetic testing has many benefits, including reassuring patients when results are normal, identifying disorders for which prenatal treatment may provide benefit, optimizing neonatal outcomes by ensuring the appropriate location for delivery and the necessary personnel to care for affected infants, and allowing the opportunity for pregnancy termination.The purpose of this Practice Bulletin is to review the current status of prenatal genetic diagnostic testing and the evidence supporting its use. For information regarding screening for fetal aneuploidy, refer to Practice Bulletin No. 163, Screening for Fetal Aneuploidy. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 40% |
| Colombia | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Science communicators (journalists, bloggers, editors) | 1 | 20% |
| Scientists | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 178 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Unknown | 176 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 24 | 13% |
| Student > Master | 22 | 12% |
| Researcher | 17 | 10% |
| Student > Ph. D. Student | 15 | 8% |
| Student > Bachelor | 11 | 6% |
| Other | 37 | 21% |
| Unknown | 52 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 56 | 31% |
| Biochemistry, Genetics and Molecular Biology | 23 | 13% |
| Nursing and Health Professions | 14 | 8% |
| Agricultural and Biological Sciences | 6 | 3% |
| Social Sciences | 4 | 2% |
| Other | 14 | 8% |
| Unknown | 61 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 30. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2023.
All research outputs
#1,307,182
of 25,374,647 outputs
Outputs from Obstetrics & Gynecology
#953
of 8,949 outputs
Outputs of similar age
#21,923
of 311,864 outputs
Outputs of similar age from Obstetrics & Gynecology
#25
of 141 outputs
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So far Altmetric has tracked 8,949 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.0. This one has done well, scoring higher than 89% of its peers.
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