| Title |
Unsolicited genomic findings in daily clinical practice
|
|---|---|
| Published in |
Nederlands Tijdschrift voor Geneeskunde, June 2018
|
| Pubmed ID | |
| Authors |
Roel H P Wouters, Rhodé M Bijlsma, Emile E Voest, Annelien L Bredenoord |
| Abstract |
Whole genome sequencing (WGS) is increasingly being used in clinical practice. As a result, various healthcare professionals now encounter ethical dilemmas that were formerly confined within the genetics clinic. In addition to autonomy and well-being of both patients and their family members, which need to be balanced carefully, a societal perspective is also vital to ensure the ethically sound introduction of whole genome sequencing into daily practice. Important choices to be made are: who is eligible for whole genome sequencing; how can informed consent be sensibly obtained, when dealing with such vast quantities of genomic information; which type of information should be offered to patients; should professionals actively search for pathogenic mutations. The rise of WGS has an impact on the moral responsibilities incumbent on healthcare professionals and necessitates a comprehensive societal debate on the advent of personalized medicine. |
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 July 2018.
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#22,767,715
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Outputs from Nederlands Tijdschrift voor Geneeskunde
#757
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#299,874
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Outputs of similar age from Nederlands Tijdschrift voor Geneeskunde
#7
of 12 outputs
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