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Mendeley readers
Attention Score in Context
| Title |
Presynaptic peptidergic modulation of olfactory receptor neurons in Drosophila
|
|---|---|
| Published in |
Proceedings of the National Academy of Sciences of the United States of America, August 2009
|
| DOI | 10.1073/pnas.0813004106 |
| Pubmed ID | |
| Authors |
Rickard Ignell, Cory M. Root, Ryan T. Birse, Jing W. Wang, Dick R. Nässel, Åsa M. E. Winther |
| Abstract |
The role of classical neurotransmitters in the transfer and processing of olfactory information is well established in many organisms. Neuropeptide action, however, is largely unexplored in any peripheral olfactory system. A subpopulation of local interneurons (LNs) in the Drosophila antannal lobe is peptidergic, expressing Drosophila tachykinins (DTKs). We show here that olfactory receptor neurons (ORNs) express the DTK receptor (DTKR). Using two-photon microscopy, we found that DTK applied to the antennal lobe suppresses presynaptic calcium and synaptic transmission in the ORNs. Furthermore, reduction of DTKR expression in ORNs by targeted RNA interference eliminates presynaptic suppression and alters olfactory behaviors. We detect opposite behavioral phenotypes after reduction and over expression of DTKR in ORNs. Our findings suggest a presynaptic inhibitory feedback to ORNs from peptidergic LNs in the antennal lobe. |
Mendeley readers
The data shown below were compiled from readership statistics for 184 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 7 | 4% |
| United States | 1 | <1% |
| Sweden | 1 | <1% |
| France | 1 | <1% |
| Unknown | 174 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 53 | 29% |
| Researcher | 52 | 28% |
| Student > Master | 17 | 9% |
| Student > Bachelor | 11 | 6% |
| Professor > Associate Professor | 9 | 5% |
| Other | 23 | 13% |
| Unknown | 19 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 105 | 57% |
| Neuroscience | 31 | 17% |
| Biochemistry, Genetics and Molecular Biology | 15 | 8% |
| Engineering | 3 | 2% |
| Environmental Science | 1 | <1% |
| Other | 7 | 4% |
| Unknown | 22 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 August 2009.
All research outputs
#16,741,542
of 24,625,114 outputs
Outputs from Proceedings of the National Academy of Sciences of the United States of America
#91,769
of 101,438 outputs
Outputs of similar age
#99,512
of 116,556 outputs
Outputs of similar age from Proceedings of the National Academy of Sciences of the United States of America
#614
of 706 outputs
Altmetric has tracked 24,625,114 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 101,438 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 38.8. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 116,556 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 706 others from the same source and published within six weeks on either side of this one. This one is in the 3rd percentile – i.e., 3% of its contemporaries scored the same or lower than it.