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Mendeley readers
Attention Score in Context
| Title |
The influence of the microenvironment on the malignant phenotype
|
|---|---|
| Published in |
Trends in Molecular Medicine, August 2000
|
| DOI | 10.1016/s1357-4310(00)01756-1 |
| Pubmed ID | |
| Authors |
Catherine C Park, Mina J Bissell, Mary Helen Barcellos-Hoff |
| Abstract |
Normal tissue homeostasis is maintained by dynamic interactions between epithelial cells and their microenvironment. As tissue becomes cancerous, there are reciprocal interactions between neoplastic cells, adjacent normal cells such as stroma and endothelium, and their microenvironments. The current dominant paradigm wherein multiple genetic lesions provide both the impetus for, and the Achilles heel of, cancer might be inadequate to understand cancer as a disease process. In the following brief review, we will use selected examples to illustrate the influence of the microenvironment in the evolution of the malignant phenotype. We will also discuss recent studies that suggest novel therapeutic interventions might be derived from focusing on microenvironment and tumor cells interactions. |
Mendeley readers
The data shown below were compiled from readership statistics for 130 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 2% |
| United States | 2 | 2% |
| Italy | 1 | <1% |
| Belgium | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 123 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 33 | 25% |
| Researcher | 23 | 18% |
| Student > Master | 16 | 12% |
| Student > Bachelor | 14 | 11% |
| Professor > Associate Professor | 13 | 10% |
| Other | 19 | 15% |
| Unknown | 12 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 49 | 38% |
| Biochemistry, Genetics and Molecular Biology | 28 | 22% |
| Medicine and Dentistry | 18 | 14% |
| Engineering | 6 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 3% |
| Other | 12 | 9% |
| Unknown | 13 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 October 2021.
All research outputs
#3,622,206
of 25,374,647 outputs
Outputs from Trends in Molecular Medicine
#484
of 1,931 outputs
Outputs of similar age
#3,416
of 38,134 outputs
Outputs of similar age from Trends in Molecular Medicine
#1
of 8 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,931 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.0. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 38,134 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them