Title |
Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study
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Published in |
Journal of Translational Medicine, January 2014
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DOI | 10.1186/1479-5876-12-9 |
Pubmed ID | |
Authors |
Wanda K O’Neal, Wayne Anderson, Patricia V Basta, Elizabeth E Carretta, Claire M Doerschuk, R Graham Barr, Eugene R Bleecker, Stephanie A Christenson, Jeffrey L Curtis, Meilan K Han, Nadia N Hansel, Richard E Kanner, Eric C Kleerup, Fernando J Martinez, Bruce E Miller, Stephen P Peters, Stephen I Rennard, Mary Beth Scholand, Ruth Tal-Singer, Prescott G Woodruff, David J Couper, Sonia M Davis |
Abstract |
As a part of the longitudinal Chronic Obstructive Pulmonary Disease (COPD) study, Subpopulations and Intermediate Outcome Measures in COPD study (SPIROMICS), blood samples are being collected from 3200 subjects with the goal of identifying blood biomarkers for sub-phenotyping patients and predicting disease progression. To determine the most reliable sample type for measuring specific blood analytes in the cohort, a pilot study was performed from a subset of 24 subjects comparing serum, Ethylenediaminetetraacetic acid (EDTA) plasma, and EDTA plasma with proteinase inhibitors (P100). |
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Unknown | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Canada | 1 | 1% |
Unknown | 77 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 22 | 28% |
Student > Ph. D. Student | 14 | 18% |
Professor | 9 | 12% |
Student > Master | 9 | 12% |
Student > Bachelor | 5 | 6% |
Other | 13 | 17% |
Unknown | 6 | 8% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 16 | 21% |
Biochemistry, Genetics and Molecular Biology | 10 | 13% |
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Engineering | 4 | 5% |
Other | 13 | 17% |
Unknown | 8 | 10% |